Glycolax

Constipation, Exophthalmos, Bowel preparation therapy + 8 more

Treatment

3 FDA approvals

20 Active Studies for Glycolax

What is Glycolax

Polyethylene glycol

The Generic name of this drug

Treatment Summary

Polyethylene glycol (PEG) is a synthetic polymer made up of ethylene oxide molecules linked together. It is soluble in water and can form hydrogen bonds with other molecules. The physical and chemical properties of PEGs vary depending on their molecular weight, with lighter molecules remaining liquid and heavier molecules becoming waxy solids. The two most common forms of PEG are PEG 3350 and PEG 400. PEGs have been used in medical treatments for a long time, mainly to relieve constipation and help with colonoscopy preparation. The reason for the use of PEG is because it binds with water, is

GoLYTELY

is the brand name

Glycolax Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

GoLYTELY

Polyethylene glycol

1984

207

Approved as Treatment by the FDA

Polyethylene glycol, also known as GoLYTELY, is approved by the FDA for 3 uses such as Constipation and Constipation .

Constipation

Constipation

Constipation

Effectiveness

How Glycolax Affects Patients

PEG 3350 is a laxative that causes watery diarrhea. Effects usually start 1-2 hours after taking it. It can be used to clear out the colon before a colonscopy, with electrolytes typically added to the dosage to prevent dehydration. When buying it over-the-counter, it does not contain any salts that can be absorbed by the body. Studies have shown that PEG 3350 has minimal effects on the body's ability to absorb fluids or create an electrochemical gradient in the colon.

How Glycolax works in the body

Osmotic laxatives are drugs that help draw water into the intestines, causing stools to become softer and easier to pass. Polyethylene glycol is a common osmotic laxative that helps draw water into the large intestine, making stools softer and easier to pass.

When to interrupt dosage

The suggested dosage of Glycolax is contingent upon the identified condition, for instance Dry Eye Syndrome, Bowel preparation therapy and Chronic Constipation. Dosage also depends on the delivery technique indicated in the table beneath.

Condition

Dosage

Administration

Dry Eye Syndrome

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Colon Cleansing for Colonoscopy

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Constipation

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Colonoscopy

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Constipation

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Exophthalmos

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Dry Eye Syndrome

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Bowel preparation therapy

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Chronic Constipation

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Obesity

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Eye

, 1.7 mg/mg, 236.0 mg/mL, 17000.0 mg, 1700.0 mg/hour, 420.0 mg/mL, 17.0 mg/mg, 2.4 mg/mg, 4.2 mg/mg, 2.36 mg/mg, 227.1 mg/mL, 210.0 mg/mL, 1.0 mg/mg, 0.55 mg/mg, 100.0 %, 1.0 %, 15.0 %, 236000.0 mg, 59550.0 mg, 238180.0 mg, 14750.0 mg, 59000.0 mg, 240.0 mg/mL, 10.0 mg/mL, 150.0 mg/mL, 210000.0 mg, 0.15 mg/mg, 100.0 mg/mL, 40000.0 mg, 60.0 mg/mL, 100000.0 mg, 0.2 %, 140000.0 mg, 17000.0 mg/dose, 160.0 mg/mL, 0.152 mg/mg, 0.85769 mg/mg, 59.55 mg/mL, 2.388 mg/mg, 2.382 mg/mg

Oral, , Powder, for solution, Powder, for solution - Oral, Powder, Powder - Oral, Powder, for solution - Topical, Topical, Cream, Cream - Topical, Liquid, Liquid - Ophthalmic, Ophthalmic, Gel - Nasal, Gel, Kit; Powder, for solution; Tablet, delayed release - Oral, Nasal, Spray, Gel - Topical, Solution, Solution - Oral, Liquid - Oral, Powder - Topical, Aerosol, metered - Nasal, Aerosol, metered, Powder, for suspension - Oral, Spray - Nasal, Kit - Oral, Kit, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Kit - Oral; Topical, Oral; Topical, Nasogastric, Powder, for solution - Nasogastric, Oral; Rectal, Powder, for suspension, Kit; Powder, for solution; Tablet, delayed release, Spray, metered, Spray, metered - Nasal, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Warnings

Glycolax has six contraindications, and it should not be employed simultaneously with any of the conditions enumerated in the following table.

Glycolax Contraindications

Condition

Risk Level

Notes

Toxic colitis

Do Not Combine

Intestinal Perforation

Do Not Combine

Megacolon, Toxic

Do Not Combine

Gastric Retention

Do Not Combine

Gastrointestinal obstruction

Do Not Combine

Ileus

Do Not Combine

There are 20 known major drug interactions with Glycolax.

Common Glycolax Drug Interactions

Drug Name

Risk Level

Description

Bisacodyl

Major

The risk or severity of mucosal ulceration and ischemic colitis can be increased when Polyethylene glycol is combined with Bisacodyl.

Bisoxatin

Major

The risk or severity of mucosal ulceration and ischemic colitis can be increased when Polyethylene glycol is combined with Bisoxatin.

Dantron

Major

The risk or severity of mucosal ulceration and ischemic colitis can be increased when Polyethylene glycol is combined with Dantron.

Deacetylbisacodyl

Major

The risk or severity of mucosal ulceration and ischemic colitis can be increased when Polyethylene glycol is combined with Deacetylbisacodyl.

Oxyphenisatin

Major

The risk or severity of mucosal ulceration and ischemic colitis can be increased when Polyethylene glycol is combined with Oxyphenisatin.

Glycolax Toxicity & Overdose Risk

The toxic dose of PEG 3350 in rats is 22000 mg/kg. If someone is suspected of overdosing on polyethylene glycols, they may experience severe diarrhea. Treatment should consist of providing supportive care.

image of a doctor in a lab doing drug, clinical research

Glycolax Novel Uses: Which Conditions Have a Clinical Trial Featuring Glycolax?

67 active clinical trials are presently examining the potential of Glycolax to provide Bowel Preparation Therapy, Body Weight stabilization for individuals over 20kg, and relief for Exophthalmos.

Condition

Clinical Trials

Trial Phases

Exophthalmos

2 Actively Recruiting

Phase 2, Phase 3

Constipation

17 Actively Recruiting

Phase 2, Not Applicable, Phase 4, Phase 3

Constipation

0 Actively Recruiting

Colon Cleansing for Colonoscopy

0 Actively Recruiting

Eye

0 Actively Recruiting

Chronic Constipation

1 Actively Recruiting

Not Applicable

Dry Eye Syndrome

8 Actively Recruiting

Phase 1, Phase 4, Not Applicable, Phase 2, Phase 3

Bowel preparation therapy

1 Actively Recruiting

Phase 1, Phase 2

Obesity

0 Actively Recruiting

Dry Eye Syndrome

6 Actively Recruiting

Phase 4, Not Applicable, Phase 2

Colonoscopy

3 Actively Recruiting

Not Applicable

Glycolax Reviews: What are patients saying about Glycolax?

5

Patient Review

12/12/2007

Glycolax for Incomplete or Infrequent Bowel Movements

It took a little over two weeks for this medication to work for my son, but it did eventually help with his constipation. We had to use it daily for seven months. The measuring cup they provided didn't have low enough measurements, so I had to get instructions on how to measure the correct amount in grams.

5

Patient Review

11/26/2007

Glycolax for Incomplete or Infrequent Bowel Movements

This product has been a godsend for me. I have diverticulosis, which previously resulted in me having to use the bathroom 5-7 times a day with cramping. This product has evened out my bowels and eliminated the cramping, allowing me to live a much more normal life.

5

Patient Review

4/29/2008

Glycolax for Incomplete or Infrequent Bowel Movements

At first, this product was effective, but now it's lost its potency. I've tried increasing my dosage to no avail. I recently heard from a reliable source that this medication is derived from plastic-- does anyone know if that's true? The name seems to suggest so

5

Patient Review

6/11/2009

Glycolax for Incomplete or Infrequent Bowel Movements

I started taking this medication to help with the constipation I experience as a result of other pain medications. It was effective for me within three days, and I've been using it regularly since then without any issues.

5

Patient Review

2/4/2008

Glycolax for Incomplete or Infrequent Bowel Movements

This product has helped me immensely. I used to have a lot of trouble going to the bathroom, but since using this treatment daily, it's been a much smoother process.

5

Patient Review

5/3/2010

Glycolax for Incomplete or Infrequent Bowel Movements

This medication made my chronic diarrhea and dumping syndrome much worse. I stopped taking it as soon as I could and am now seeking out a new doctor.

5

Patient Review

12/15/2007

Glycolax for Incomplete or Infrequent Bowel Movements

IBS has been a thorn in my side for years, but this treatment has really made a world of difference.

4.7

Patient Review

2/1/2008

Glycolax for Incomplete or Infrequent Bowel Movements

This medication has helped me a lot. I don't get constipated nearly as often, and when I do it's not nearly as bad. My doctor says I should take this every day for the best results, and that's what I've been doing.

4.7

Patient Review

6/8/2011

Glycolax for Incomplete or Infrequent Bowel Movements

I've been on this medication for a while now, because nothing else has helped with my chronic constipation. My doctor says it's okay to be on the medicine long-term; it just goes right through your system and won't create dependence. Additionally, I haven't experienced any side effects, which is great.

4.7

Patient Review

9/14/2009

Glycolax for Incomplete or Infrequent Bowel Movements

This medication has been excellent for my chronic constipation and impaction due to pain medication. I've been taking it for years and have recommended it to others with great results. However, I am concerned about the long-term effects as I was told it is related to antifreeze? If anyone could provide more information on the safety of this product, that would be much appreciated.

3.7

Patient Review

9/26/2009

Glycolax for Incomplete or Infrequent Bowel Movements

This product is effective if you are constipated. I use it every day because I was born without a large intestine. It works well for me, but if you are severely constipated, this may not be the right solution for you.

3.3

Patient Review

1/19/2008

Glycolax for Incomplete or Infrequent Bowel Movements

GlycoLax is an effective constipation treatment that I've been using for a while now. It's easy to take and works well.

3.3

Patient Review

11/17/2007

Glycolax for Incomplete or Infrequent Bowel Movements

2.3

Patient Review

3/16/2012

Glycolax for Incomplete or Infrequent Bowel Movements

This treatment didn't help me at all.

2

Patient Review

11/18/2007

Glycolax for Incomplete or Infrequent Bowel Movements

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about glycolax

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are Glycolax and Miralax the same?

"(n.d.). Harvard Health.

Polyethylene glycol is a drug that is used as a laxative. The most common side effect of this drug is abdominal cramping. Other side effects include bloating, gas, and diarrhea. This drug is available in over-the-counter products."

Answered by AI

What are the side effects of Glycolax?

"Symptoms of a serious reaction include severe or bloody diarrhea, rectal bleeding, blood in your stools, or severe and worsening stomach pain."

Answered by AI

What is GlycoLax used for?

"This medication can be used to treat occasional constipation. It works by holding water in the stool and making the stool softer. This makes it easier to have a bowel movement. This medication is also available without a prescription."

Answered by AI

Can you buy Glycolax over-the-counter?

"Glycolax is an over-the-counter laxative that is brand-name and helps with relieving constipation. Constipation is when the bowels are not emptying because of hard stools."

Answered by AI

Clinical Trials for Glycolax

Image of Eye Research Foundation /ID# 267931 in Newport Beach, United States.

ABBV-444 for Dry Eye Syndrome

18+
All Sexes
Newport Beach, CA

Dry Eye Disease (DED) refers to a long-term condition that happens when there is not enough lubrication in your eyes. This can happen when your eye cannot make enough tears or if you make poor-quality tears. The purpose of this study is to compare the efficacy and safety of a new artificial tear formulation (ABBV-444) with Refresh Optive UD for 90 days in participants with Dry Eye Disease (DED. ABBV-444 is being developed for the treatment of Dry Eye Disease (DED). Participants will be placed into 1 of 2 treatment arms. Each group receives different treatment. Adult participants diagnosed with dry eye disease will be enrolled. Around 250 participants will be enrolled in the study at approximately 20 sites across the US In this study, participants first complete a 7-day run-in period using REFRESH PLUS® eye drops. Those eligible are then randomized to receive ABBV-444 eye drops or REFRESH OPTIVE® Unit Dose eye drops. Participants in both arms will receive treatment for a 90-day treatment period. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend multiple required study visits during the study at the study site. The effect of the treatment will be checked by medical assessments and questionnaires.

Phase 3
Recruiting

Eye Research Foundation /ID# 267931 (+9 Sites)

ABBVIE INC.

AbbVie

Image of Center for Sight in Las Vegas, United States.

Acoltremon for Dry Eye Syndrome

18+
All Sexes
Las Vegas, NV

Dry eye disease (DED) is a common, chronic and multifactorial disease of the ocular surface presenting with signs and symptoms of ocular discomfort, visual disturbance and fluctuation, tear film instability, ocular surface inflammation and damage. It significantly affects patients' quality of life and is one of the most frequent reasons for visits to eye care providers. Many patients remain symptomatic in real-world settings despite current pharmacologic therapeutic options available. As symptoms often lag behind ocular signs, a 3 month study with multiple time points has been designed to assess short term and mid-term symptomatic changes. This study will use Dry Eye Surveys to evaluate Acoltremon in Real World Settings to help understand its real world effectiveness and potential to improve symptoms in dry eye patients.

Phase 4
Waitlist Available

Center for Sight

Image of Kannar Eye Care in Pittsburg, United States.

Acoltremon for Dry Eye Syndrome

18 - 75
All Sexes
Pittsburg, KS

This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina (Minneapolis, MN). Adults ≥18 years of age who have been diagnosed with DED for at least 6 months and who are currently symptomatic (Eye Dryness VAS Score ≥40) will be recruited. Subjects will have an abnormal Schirmer test of \<10 mm/5 min. Subjects will also be required to score ≤70 on the IDEEL Quality of Life (QoL) Work domain to ensure that their DED symptoms are significantly impacting their ability to do work.9 Subjects will be required to have corrected distance visual acuity of 20/32 (0.2 logMAR) or better.

Phase 4
Recruiting

Kannar Eye Care (+2 Sites)

Have you considered Glycolax clinical trials?

We made a collection of clinical trials featuring Glycolax, we think they might fit your search criteria.
Go to Trials

Have you considered Glycolax clinical trials?

We made a collection of clinical trials featuring Glycolax, we think they might fit your search criteria.
Go to Trials

Have you considered Glycolax clinical trials?

We made a collection of clinical trials featuring Glycolax, we think they might fit your search criteria.
Go to Trials