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- Alzheimer's Disease
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- Heart Disease
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183 Down Syndrome Trials Near You
Power is an online platform that helps thousands of Down Syndrome patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerImlifidase for Goodpasture Syndrome
Trial Details
Key Eligibility Criteria
50 Participants Needed
Blinatumomab + Chemotherapy for Leukemia
Trial Details
Key Eligibility Criteria
6720 Participants Needed
Xenon for Out-of-Hospital Cardiac Arrest
Trial Details
Key Eligibility Criteria
1436 Participants Needed
Trial Details
Key Eligibility Criteria
280 Participants Needed
Ivosidenib + Azacitidine for MDS
Trial Details
Key Eligibility Criteria
48 Participants Needed
Trial Details
Key Eligibility Criteria
360 Participants Needed
Cedazuridine + Azacitidine for Leukemia
Trial Details
Key Eligibility Criteria
235 Participants Needed
Imetelstat for Myelodysplastic Syndrome
Trial Details
Key Eligibility Criteria
289 Participants Needed
Zorevunersen for Dravet Syndrome
Trial Details
Key Eligibility Criteria
150 Participants Needed
LP352 for Dravet Syndrome
Trial Details
Key Eligibility Criteria
160 Participants Needed
Luspatercept for Myelodysplastic Syndrome
Trial Details
Key Eligibility Criteria
100 Participants Needed
Venetoclax + Azacitidine for Myelodysplastic Syndrome
Trial Details
Key Eligibility Criteria
53 Participants Needed
Pomalidomide + Chemotherapy for Acute Myeloid Leukemia
Trial Details
Key Eligibility Criteria
50 Participants Needed
Diagnostic Testing for Pediatric Leukemia
Trial Details
Key Eligibility Criteria
960 Participants Needed
Sirolimus for Cowden Syndrome with Colon Polyposis
Trial Details
Key Eligibility Criteria
10 Participants Needed
Venetoclax + Chemotherapy for Richter's Syndrome
Trial Details
Key Eligibility Criteria
69 Participants Needed
Pacritinib for VEXAS Syndrome
Trial Details
Key Eligibility Criteria
78 Participants Needed
AK117 + Azacitidine for Myelodysplastic Syndrome
Trial Details
Key Eligibility Criteria
90 Participants Needed
EPX-100 for Dravet Syndrome
Trial Details
Key Eligibility Criteria
100 Participants Needed
Trial Details
Key Eligibility Criteria
74 Participants Needed
Why Other Patients Applied
"My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."
"I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."
"As a healthy volunteer, I like to participate in as many trials as I'm able to. It's a good way to help research and earn money."
"I have dealt with voice and vocal fold issues related to paralysis for over 12 years. This problem has negatively impacted virtually every facet of my life. I am an otherwise healthy 48 year old married father of 3 living. My youngest daughter is 12 and has never heard my real voice. I am now having breathing issues related to the paralysis as well as trouble swallowing some liquids. In my research I have seen some recent trials focused on helping people like me."
"I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."
RAY121 for Immune System Disorders
Trial Details
Key Eligibility Criteria
144 Participants Needed
CC-91633 for Leukemia
Trial Details
Key Eligibility Criteria
180 Participants Needed
JNJ-74856665 for AML and MDS
Trial Details
Key Eligibility Criteria
153 Participants Needed
Safflower Oil + Soy Pretzels for Metabolic Syndrome
Trial Details
Key Eligibility Criteria
20 Participants Needed
Tamibarotene + Azacitidine for Myelodysplastic Syndrome
Trial Details
Key Eligibility Criteria
550 Participants Needed
Cochlear Implant Stimulation for Usher Syndrome
Trial Details
Key Eligibility Criteria
44 Participants Needed
SPI-62 for Cushing's Syndrome
Trial Details
Key Eligibility Criteria
30 Participants Needed
Dilated vs Non-Dilated Eye Exams for Down Syndrome
Trial Details
Key Eligibility Criteria
40 Participants Needed
Lyme Disease Vaccine for Healthy Children
Trial Details
Key Eligibility Criteria
3235 Participants Needed
VX-147 for Kidney Disease
Trial Details
Key Eligibility Criteria
466 Participants Needed
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Learn More About Power
We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
Frequently Asked Questions
How much do Down Syndrome clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Down Syndrome clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Down Syndrome trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Down Syndrome is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Down Syndrome medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Down Syndrome clinical trials?
Most recently, we added Gene Therapy for Charcot-Marie-Tooth Disease, Xenon for Out-of-Hospital Cardiac Arrest and Bowel Management Program for Colorectal Cancer to the Power online platform.