← Back to Search

Optical Correction

Dilated vs Non-Dilated Eye Exams for Down Syndrome

Phase 2

Recruiting

Led By Heather Anderson, OD, PhD

Research Sponsored by Ohio State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 day

Awards & highlights

Study Summary

This trial is testing whether dilation is necessary to get an accurate measure of HOAs in people with Down syndrome.

Who is the study for?

This trial is for individuals with Down Syndrome who can have their eyes dilated, fixate on objects for study measures, and respond to visual acuity testing. It's not suitable for those with involuntary eye movements (ocular nystagmus), past eye surgeries (except strabismus surgery), or conditions like corneal or lenticular opacities and other ocular diseases.Check my eligibility

What is being tested?

The study is examining whether dilating the eyes before measuring wavefront errors (distortions in vision) provides a better basis for prescribing glasses compared to non-dilated measurements. This could help improve vision correction in people with Down Syndrome.See study design

What are the potential side effects?

Eye dilation may cause temporary sensitivity to light, blurred vision close-up, and possibly discomfort from the bright lights used during examination. These effects typically subside after a few hours.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 day

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 day

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Distance Visual Acuity

Secondary outcome measures

Near Visual Acuity

Participant distance vision ranking

Participant near vision ranking

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Non-dilated first, dilated secondExperimental Treatment2 Interventions

Each participant will perform vision testing first through a prescription determined from wavefront measurements obtained before dilation. Second, each participation will perform vision testing through a prescription determined from wavefront measurements obtained after dilation.

Group II: Dilated first, non-dilated secondExperimental Treatment2 Interventions

Each participant will perform vision testing first through a prescription determined from wavefront measurements obtained after dilation. Second, each participation will perform vision testing through a prescription determined from wavefront measurements obtained before dilation.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Ohio State UniversityLead Sponsor

829 Previous Clinical Trials

505,703 Total Patients Enrolled

1 Trials studying Refractive Errors

294 Patients Enrolled for Refractive Errors

University of HoustonOTHER

147 Previous Clinical Trials

47,442 Total Patients Enrolled

1 Trials studying Refractive Errors

294 Patients Enrolled for Refractive Errors

Heather Anderson, OD, PhDPrincipal InvestigatorOhio State University

Media Library

$Dilated Refraction (Optical Correction) Clinical Trial Eligibility Overview. Trial Name: NCT05059041 — Phase 2$

$Refractive Errors Research Study Groups: Dilated first, non-dilated second, Non-dilated first, dilated second$

$Refractive Errors Clinical Trial 2023: Dilated Refraction Highlights & Side Effects. Trial Name: NCT05059041 — Phase 2$

$Dilated Refraction (Optical Correction) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05059041 — Phase 2$

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What possible risks accompany Non-Dilated Refraction?

"While Phase 2 clinical trials have yet to produce evidence of Non-Dilated Refraction's efficacy, the available data does suggest that it is safe. For this reason, our team at Power has rated its safety a 2 on a scale from 1 to 3."

Answered by AI

Are opportunities available for individuals to participate in this experiment?

"Affirmative. According to clinicaltrials.gov, the trial first appeared on May 6th 2022 and was most recently modified 10 days later. 40 participants are required between two medical sites for successful completion of this experiment."

Answered by AI

How many participants are taking part in this experimental program?

"Yes, according to clinicaltrials.gov the trial that first went live on May 6th 2022 is currently looking for volunteers. The study needs a total of 40 participants from two different sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome

Heather Anderson OD, PhD 2022. "Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05059041.

All > Down Syndrome