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Mitiperstat for COPD (CRESCENDO Trial)
CRESCENDO Trial Summary
This trial will test a drug to see if it can help adults with COPD feel better and be safe.
CRESCENDO Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowCRESCENDO Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.CRESCENDO Trial Design
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Who is running the clinical trial?
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- I am between 40 and 80 years old.I have been diagnosed with moderate to severe COPD.I don't have any health issues that could make the study unsafe for me or affect the results.I have a significant lung condition that is not COPD.I have smoked at least 10 packs of cigarettes a year.I have asthma or had it after turning 25.Your body mass index (BMI) is between 18 and 40.I am at high risk of lung issues due to frequent coughs or severe breathing test results.I haven't had a serious infection needing long-term medication in the last 4 weeks.I have been on a stable medication regimen for my condition for at least 3 months.
- Group 1: Mitiperstat (AZD4831)
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are my qualifications suitable for enrollment in this research project?
"To take part in this clinical trial, participants must have a diagnosis of chronic obstructive airway disease and be between 40-80 years old. 288 individuals are needed for the completion of this study."
How many treatment centers in the United States are conducting this clinical trial?
"Currently, 15 clinical trial sites are recruiting participants. Said locations encompass Newport Beach, Clearwater and Lake Wales amongst other cities. Thus it is beneficial to pick the closest clinic if you decide to partake in this study so that travel is kept at a minimum."
Could you provide insight into the risks associated with AZD4831?
"Our experts at Power have given AZD4831 a score of 2 on their safety scale, as this is only in Phase 2 trials and there has been no evidence yet that it is effective."
Are elderly individuals being accepted into this experiment?
"This medical study has a limited age range of 40 to 80 years old. There are 35 trials for younger individuals and 467 studies available to those over 65."
Are there any participation slots open for this trial?
"Per the details on clinicaltrials.gov, this medical trial is still seeking participants. Initially posted in November of 2022, it was most recently updated in December of that same year."
How many individuals are allowed to register for the experiment?
"Affirmative. Per the details listed on clinicaltrials.gov, this research is actively enrolling participants with an original posting date of November 14th 2022 and a most recent update on December 12th 2022. The study requires 288 individuals across 15 different sites to volunteer for it."
Who else is applying?
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What portion of applicants met pre-screening criteria?
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