Trials in Chicago, Illinois
Here are the top 10 medical studies for depression in Chicago, Illinois
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Phase 3 Trials
Investigational Drug for Bipolar Depression
Recruiting1 awardPhase 3
Warrenville, Illinois
This trial is testing a new medication called SEP-4199 CR to see if it can help adults aged 18-65 who have depression from Bipolar I disorder. The study will compare the effects of the medication to see if it reduces symptoms of depression. SEP-4199 has shown antidepressant efficacy in a previous study for bipolar depression.
Psychedelic
Psilocybin for Treatment-Resistant Depression
Recruiting1 awardPhase 3
Chicago, Illinois
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
Aticaprant for Major Depressive Disorder
Recruiting1 awardPhase 3
Chicago, Illinois
This trial is testing aticaprant to see if it can help people with major depressive disorder who still feel very down and don't enjoy things despite taking other antidepressants. The study focuses on adults who haven't responded well to their current treatments. Aticaprant works by blocking a specific brain receptor, which might help improve their mood and reduce depressive symptoms.
NMRA-335140 for Depression
Recruiting2 awardsPhase 3
Chicago, Illinois
This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.
Trials With No Placebo
Psychedelic
Psilocybin for Depression and Personality Disorders
Recruiting1 awardPhase 2
Chicago, Illinois
This trial tests psilocybin, a compound from certain mushrooms, on adults with major depressive disorder and borderline personality disorder. It aims to see if psilocybin can improve mood and reduce symptoms by affecting brain chemicals. Psilocybin has shown promise as a treatment for major depressive disorder and has been designated as a breakthrough therapy by the FDA.
Behavioural Intervention
Digital Mental Health Intervention for Self-Harm
Recruiting1 award
Chicago, Illinois
This trial tests a digital mental health app for young adults who self-injure but aren't in treatment. The app offers educational content and activities, with some users also getting support from coaches. The goal is to see if the app is feasible for a larger study.
Behavioral Intervention
Cognitive Behavioral Therapy for Adolescent Depression
Recruiting1 award2 criteria
Chicago, Illinois
This trial aims to prevent depression in at-risk teenagers using the CATCH-IT program. The program teaches skills to manage thoughts, behaviors, and relationships through various therapies. The goal is to make the program effective, easy to use, and widely available. CATCH-IT is an online depression prevention intervention that has been tested in various studies for its effectiveness in preventing depressive episodes among adolescents.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.