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UT Southwestern/Simmons Cancer Center-Dallas

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Dallas, Texas 75390

Global Leader in Brain Tumor

Global Leader in Cancer

Conducts research for Lung Cancer

Conducts research for Leukemia

Conducts research for Lymphoma

688 reported clinical trials

69 medical researchers

Photo of UT Southwestern/Simmons Cancer Center-Dallas in DallasPhoto of UT Southwestern/Simmons Cancer Center-Dallas in DallasPhoto of UT Southwestern/Simmons Cancer Center-Dallas in Dallas

Summary

UT Southwestern/Simmons Cancer Center-Dallas is a medical facility located in Dallas, Texas. This center is recognized for care of Brain Tumor, Cancer, Lung Cancer, Leukemia, Lymphoma and other specialties. UT Southwestern/Simmons Cancer Center-Dallas is involved with conducting 688 clinical trials across 639 conditions. There are 69 research doctors associated with this hospital, such as Martha M. Pacheco, David Miller, MD, Matthew Campbell, MD, and Syed M. Kazmi.

Area of expertise

1

Brain Tumor

Global Leader

UT Southwestern/Simmons Cancer Center-Dallas has run 84 trials for Brain Tumor. Some of their research focus areas include:

Stage IV
Stage II
Stage I
2

Cancer

Global Leader

UT Southwestern/Simmons Cancer Center-Dallas has run 84 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage II

Top PIs

Clinical Trials running at UT Southwestern/Simmons Cancer Center-Dallas

Lung Cancer

Bladder Cancer

Kidney Cancer

Prostate Cancer

Skin Cancer

Bladder Carcinoma

Brain Tumor

Uterine Cancer

Cancer

Esophageal cancer

Image of trial facility.

Chemotherapy + Immunotherapy vs. Immunotherapy

for Advanced Lung Cancer

This phase III trial compares the effect of adding chemotherapy to immunotherapy (pembrolizumab) versus immunotherapy alone in treating patients with stage IIIB-IV lung cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab and chemotherapy may help stabilize lung cancer.

Recruiting

2 awards

Phase 3

Image of trial facility.

Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.

Recruiting

2 awards

Phase 3

31 criteria

Image of trial facility.

Thoracotomy vs Thoracoscopy

for Metastatic Osteosarcoma

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through a single larger incision (like a large cut) that goes between the ribs, opens up the chest, and removes the cancer. Thoracoscopy is a type of chest surgery where the doctor makes several small incisions and uses a small camera to help with removing the cancer. This trial is being done evaluate the two different surgery methods for patients with osteosarcoma that has spread to the lung to find out which is better.

Recruiting

2 awards

Phase 3

7 criteria

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