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UT Southwestern/Simmons Cancer Center-Dallas

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Dallas, Texas 75390
Global Leader in Brain Tumor
Global Leader in Cancer
Conducts research for Lung Cancer
Conducts research for Leukemia
Conducts research for Lymphoma
688 reported clinical trials
69 medical researchers
Photo of UT Southwestern/Simmons Cancer Center-Dallas in DallasPhoto of UT Southwestern/Simmons Cancer Center-Dallas in DallasPhoto of UT Southwestern/Simmons Cancer Center-Dallas in Dallas

Summary

UT Southwestern/Simmons Cancer Center-Dallas is a medical facility located in Dallas, Texas. This center is recognized for care of Brain Tumor, Cancer, Lung Cancer, Leukemia, Lymphoma and other specialties. UT Southwestern/Simmons Cancer Center-Dallas is involved with conducting 688 clinical trials across 641 conditions. There are 69 research doctors associated with this hospital, such as Martha M. Pacheco, David Miller, MD, Matthew Campbell, MD, and Syed M. Kazmi.

Area of expertise

1Brain Tumor
Global Leader
UT Southwestern/Simmons Cancer Center-Dallas has run 85 trials for Brain Tumor. Some of their research focus areas include:
Stage IV
Stage II
Stage I
2Cancer
Global Leader
UT Southwestern/Simmons Cancer Center-Dallas has run 80 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage I
Stage II

Top PIs

Clinical Trials running at UT Southwestern/Simmons Cancer Center-Dallas

Lung Cancer
Kidney Cancer
Skin Cancer
Prostate Cancer
Esophageal cancer
Brain Tumor
Cancer
Colorectal Cancer
Colon Cancer
Uterine Cancer
Image of trial facility.

Chemotherapy + Immunotherapy vs. Immunotherapy

for Advanced Lung Cancer

This phase III trial compares the effect of adding chemotherapy to immunotherapy (pembrolizumab) versus immunotherapy alone in treating patients with stage IIIB-IV lung cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab and chemotherapy may help stabilize lung cancer.
Recruiting2 awards Phase 3
Image of trial facility.

Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
Image of trial facility.

Crizotinib

for Non-Small Cell Lung Cancer

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-small cell lung cancer and an ALK fusion mutation.
Recruiting2 awards Phase 328 criteria

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security