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Baylor University Medical Center

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Dallas, Texas 75246
Global Leader in Acute Myelogenous Leukemia
Global Leader in Multiple Myeloma
Conducts research for Acute Myeloid Leukemia
Conducts research for Breast Cancer
Conducts research for Heart Failure
357 reported clinical trials
17 medical researchers
Photo of Baylor University Medical Center in DallasPhoto of Baylor University Medical Center in DallasPhoto of Baylor University Medical Center in Dallas

Summary

Baylor University Medical Center is a medical facility located in Dallas, Texas. This center is recognized for care of Acute Myelogenous Leukemia, Multiple Myeloma, Acute Myeloid Leukemia, Breast Cancer, Heart Failure and other specialties. Baylor University Medical Center is involved with conducting 357 clinical trials across 601 conditions. There are 17 research doctors associated with this hospital, such as Joyce O'Shaughnessy, MD, Carlos R Becerra, Susan Mathai, MD, and Andrew S Paulson, MD.

Area of expertise

1Acute Myelogenous Leukemia
Global Leader
Baylor University Medical Center has run 24 trials for Acute Myelogenous Leukemia. Some of their research focus areas include:
KMT2A positive
NPM1 positive
NPM1c positive
2Multiple Myeloma
Global Leader
Baylor University Medical Center has run 22 trials for Multiple Myeloma. Some of their research focus areas include:
Stage III
del(17/17p) positive
t(14;16) positive

Top PIs

Clinical Trials running at Baylor University Medical Center

Multiple Myeloma
Idiopathic Pulmonary Fibrosis
Interstitial Lung Disease
Lymphoma
Non-Hodgkin's Lymphoma
Post-Traumatic Stress Disorder
Heart Failure
Acute Myeloid Leukemia
Pulmonary Hypertension
Crohn's Disease
Image of trial facility.

Elranatamab Combinations

for Multiple Myeloma

The purpose of this clinical trial is to (1) learn whether the BCMA-CD3 bispecific antibody elranatamab can provide more benefit to people with multiple myeloma compared to a combination therapy including daratumumab, pomalidomide, and dexamethasone, and (2) learn about the safety and activity of elranatamab in combination with the anti-CD38 monoclonal antibody daratumumab. People with multiple myeloma who have received previous treatment including lenalidomide will be enrolled in the study. Part 1 of the study will assess the safety and activity of different doses of elranatamab in combination with daratumumab. People participating in Part 2 of the study will be randomly assigned to receive either elranatamab alone, elranatamab plus daratumumab, or daratumumab, pomalidomide, and dexamethasone. Part 2 will evaluate the safety and activity of (1) elranatamab alone compared to daratumumab, pomalidomide, and dexamethasone, and (2) elranatamab plus daratumumab. Part 3 will assess the effect of increased measures to protect against infection in people treated with either elranatamab alone or together with daratumumab. All people participating in the study will receive study treatment until their disease progresses, they experience unacceptable side effects, or they choose to no longer participate in the study.
Recruiting2 awards Phase 36 criteria
Image of trial facility.

Elranatamab

for Multiple Myeloma

The purpose of this study is to learn about the study medicine called elranatamab.This study aims to compare elranatamab to other medicines for the treatment of MM (a type of cancer). This study is seeking participants who: * Are 18 years of age or older and have MM. * Have received treatments before for MM. * Have MM that has returned or not responded to their most recent treatment. Half of the participants will receive elranatamab. The other half of participants will receive a combination therapy selected by the study doctor. The selected combination therapy will include 2 to 3 different medicines commonly used to treat MM. Elranatamab will be given as a shot under the skin at the study clinic about once a week. This may change to a smaller number of shots later in the study. The medicines in the combination therapy will be taken by mouth (at home or at the study clinic) AND will be given either as: * a shot under the skin at the study clinic * through a needle in the vein at the study clinic The number of times these medicines will be taken depends on what combination therapy the study doctor selects. Participants may continue to receive elranatamab or a combination therapy until their MM is no longer responding. The study team will see how each participant is doing with the study treatment during regular visits at the study clinic. The study team will continue to follow-up with participants after study treatment with telephone contacts (or visits). The study will compare the experiences of people receiving elranatamab to those people receiving a combination therapy. This will help learn about the safety and how effective elranatamab is.
Recruiting2 awards Phase 36 criteria
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Elranatamab vs Lenalidomide

for Multiple Myeloma

The purpose of this study is to evaluate whether elranatamab monotherapy can provide clinical benefit compared to lenalidomide monotherapy (control) in participants with newly diagnosed multiple myeloma after undergoing autologous stem cell transplant. In Part 1 and Part 2 of the study, participants in the study will either receive elranatamab (arm A and C) as an injection under the skin at the study clinic or lenalidomide orally once daily at home (arm B). Participation in the study will be approximately five years
Recruiting2 awards Phase 38 criteria

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security