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University of Texas Southwestern Medical Center

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Dallas, Texas 75390

Global Leader in Cancer

Global Leader in Lung Cancer

Conducts research for Breast Cancer

Conducts research for Depression

Conducts research for Heart Failure

2260 reported clinical trials

223 medical researchers

Photo of University of Texas Southwestern Medical Center in DallasPhoto of University of Texas Southwestern Medical Center in DallasPhoto of University of Texas Southwestern Medical Center in Dallas

Summary

University of Texas Southwestern Medical Center is a medical facility located in Dallas, Texas. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Depression, Heart Failure and other specialties. University of Texas Southwestern Medical Center is involved with conducting 2,260 clinical trials across 2,059 conditions. There are 223 research doctors associated with this hospital, such as David Miller, MD, Matthew Campbell, MD, Syed M. Kazmi, and Patrick Leavey, MD.

Area of expertise

1

Cancer

Global Leader

University of Texas Southwestern Medical Center has run 121 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
HER2 negative
2

Lung Cancer

Global Leader

University of Texas Southwestern Medical Center has run 110 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
KRAS positive

Top PIs

Clinical Trials running at University of Texas Southwestern Medical Center

Breast Cancer

Colorectal Cancer

Prostate Cancer

Kidney Cancer

Spinal Muscular Atrophy

Cystic Fibrosis

Multiple Myeloma

Chronic Lymphocytic Leukemia

Bladder Cancer

Peripheral Artery Disease

Image of trial facility.

Endocrine + CDK4/6 Inhibitor Therapy

for Breast Cancer

This trial is studying if hormone therapy and a drug that stops cell growth can improve the immune system's response against hormone-sensitive breast cancer.

Recruiting

3 awards

Phase 2

13 criteria

Image of trial facility.

Gadolinium-Based Contrast Media Effects on Motor and Cognitive Functioning

for

This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA. The study aims to create detailed images of the organs and tissue of the human body during x-ray, CT-scan or MRI investigations, doctors are using contrast media (a kind of dye) which can be given to patients by injection into a blood vessel or by mouth. In this study researchers want to find out whether so called gadolinium-based contrast agents (GBCAs) have an effect on body movement and mental skills when given to participants multiple times within 5 years. The study plans to enroll about 2076 participants suffering from a condition for which they are likely to have at least annually a MRI or another imaging examinations. Only adults up to 65 years will be considered to join this study. During the study duration of 5 years participants will receive annually a MRI or other imaging tests (such as CT-scan, x-ray) and will visit the study doctor at least 7 times for physical examinations, laboratory investigations and tests on body movement and mental skills.

Recruiting

3 awards

Phase 4

9 criteria

Image of trial facility.

sac-TMT + Pembrolizumab

for Breast Cancer

This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TPC) in participants with triple-negative breast cancer (TNBC) who received neoadjuvant therapy and did not achieve a pathological complete response (pCR) at surgery. The primary objective is to compare sacituzumab tirumotecan plus pembrolizumab to TPC (pembrolizumab or pembrolizumab plus capecitabine) with respect to invasive disease-free survival (iDFS) per investigator assessment. It is hypothesized that sacituzumab tirumotecan plus pembrolizumab is superior to TPC with respect to iDFS per investigator assessment.

Recruiting

2 awards

Phase 3

5 criteria

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