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Case Western Reserve University
Claim this profileCleveland, Ohio 44106
Global Leader in Skin Cancer
Global Leader in Relapse
Conducts research for Human Immunodeficiency Virus Infection
Conducts research for Stomach Cancer
Conducts research for Ovarian Cancer
631 reported clinical trials
65 medical researchers
Summary
Case Western Reserve University is a medical facility located in Cleveland, Ohio. This center is recognized for care of Skin Cancer, Relapse, Human Immunodeficiency Virus Infection, Stomach Cancer, Ovarian Cancer and other specialties. Case Western Reserve University is involved with conducting 631 clinical trials across 889 conditions. There are 65 research doctors associated with this hospital, such as Duncan S. Stearns, Amy Armstrong, MD, Pedro M. Barata, and Afshin Dowlati, MD.Area of expertise
1Skin Cancer
Global LeaderStage IV
Stage III
Stage I
2Relapse
Global LeaderStage IV
Stage III
Stage I
Top PIs
Duncan S. StearnsRainbow Babies and Childrens Hospital7 years of reported clinical research
Expert in Uterine Tumors
Expert in Neuroblastoma
57 reported clinical trials
118 drugs studied
Amy Armstrong, MDWashington University School of Medicine2 years of reported clinical research
Studies Relapse
Studies Osteosarcoma
26 reported clinical trials
58 drugs studied
Pedro M. BarataTulane University Health Sciences Center1 year of reported clinical research
Studies Skin Cancer
Studies Kidney Cancer
20 reported clinical trials
52 drugs studied
Afshin Dowlati, MDUniversity Hospitals Cleveland Medical Center1 year of reported clinical research
Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
19 reported clinical trials
33 drugs studied
Clinical Trials running at Case Western Reserve University
Skin Cancer
Lung Cancer
Esophageal Adenocarcinoma
Esophageal Carcinoma
Ovarian Cancer
Cancer
Gastroesophageal Junction Adenocarcinoma
Kidney Cancer
Squamous Cell Carcinoma
Uterine Tumors
Chemotherapy
for Cancer
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Drugs used in chemotherapy, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.
Recruiting2 awards Phase 326 criteria
Pump Chemotherapy
for Colorectal Cancer
This phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in addition to standard of care chemotherapy versus standard of care chemotherapy alone in treating patients with colorectal cancer that has spread to the liver (liver metastases) and cannot be removed by surgery (unresectable). HAI uses a catheter to carry a tumor-killing chemotherapy drug called floxuridine directly into the liver. HAI is already approved by the Food and Drug Administration (FDA) for use in metastatic colorectal cancer to the liver, but it is only available at a small number of hospitals, and most of the time it is not used until standard chemotherapy stops working. Standard chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Adding HAI to standard chemotherapy may be effective in shrinking or stabilizing unresectable colorectal liver metastases.
Recruiting2 awards Phase 37 criteria
Herceptin Hylecta or Phesgo + Chemotherapy
for Uterine Cancer
This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops tumor cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial cancer.
Recruiting2 awards Phase 3
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Frequently asked questions
What kind of research happens at Case Western Reserve University?
Case Western Reserve University is a medical facility located in Cleveland, Ohio. This center is recognized for care of Skin Cancer, Relapse, Human Immunodeficiency Virus Infection, Stomach Cancer, Ovarian Cancer and other specialties. Case Western Reserve University is involved with conducting 631 clinical trials across 889 conditions. There are 65 research doctors associated with this hospital, such as Duncan S. Stearns, Amy Armstrong, MD, Pedro M. Barata, and Afshin Dowlati, MD.
Where is Case Western Reserve University located?
Case Western Reserve University Hospital is located at 11100 Euclid Ave, Cleveland, OH 44106. For directions, from Interstate 90, exit at Martin Luther King Jr. Boulevard, proceed south to the East 105th traffic light, cross East 105th, and continue to Euclid Avenue. Turn left onto Euclid, then right on Adelbert Rd, and the hospital is on the left past University Hospitals.
Who should I call to ask about financial aid or insurance network?
For financial assistance at Case Western Reserve University Hospital:
- Contact the UH Customer Service Department at 216-844-8299, available Monday – Friday: 8 a.m. – 5:30 p.m.
- For insurance inquiries, reach out to UH Financial Counselors at 1-866-771-7266, Monday – Friday: 8 a.m. – 4:30 p.m.
- For detailed information on the hospital's financial assistance program, visit the UH Financial Assistance Program Overview and Financial Assistance Application available online.
What insurance does Case Western Reserve University accept?
**University Hospitals Cleveland Medical Center Insurance Information:**
- **Accepted Insurance Plans:** Aetna, Anthem, Cigna, Medical Mutual of Ohio, Molina, United Healthcare, among others.
- **Coverage Includes:** Inpatient and outpatient care, laboratory and diagnostic services, primary and specialty care, mental health/substance abuse services.
**Case Western Reserve University Student Health Plan:**
- **Insurer:** Aetna Life Insurance Company.
- **Eligibility:** Mandatory for students registered for at least one credit hour, with exceptions for certain categories of students.
- **Benefits:** Provides efficient, affordable, and effective medical coverage, with varying coverage dates.
What awards or recognition has Case Western Reserve University received?
Case Western Reserve University Hospital in Cleveland, Ohio, is renowned for its exceptional research program, especially in medicine. It boasts a Department of Medicine ranked among the top by the NIH, supported by leading scientists and cutting-edge facilities. Additionally, the hospital is actively involved in national and international clinical trials.
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Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.