Dr. Afshin Dowlati, MD
Claim this profileUniversity Hospitals Cleveland Medical Center
Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
19 reported clinical trials
33 drugs studied
Area of expertise
1Lung Cancer
Stage III
Stage II
Stage I
2Non-Small Cell Lung Cancer
Stage IV
Stage III
Stage II
Affiliated Hospitals
Clinical Trials Afshin Dowlati, MD is currently running
SW-682
for Solid Tumors
This is a first-in-human (FIH), Phase 1a/1b open-label, multicenter, dose escalation and dose expansion study of SW-682 in adult participants with metastatic or unresectable advanced solid tumors with or without Hippo pathway alterations that are refractory to, or have progressed, during or after appropriate prior systemic anticancer therapy, including chemotherapy, immunotherapy, radiation therapy or targeted therapy, or for which no treatment is available, or prior standard of care (SOC) therapy was not tolerated and for which there is no further SOC treatment available. The study includes a Part 1 (Phase 1a) dose escalation phase and a Part 2 (Phase 1b) dose expansion to optimize the dose to be used for further development. All participants will self-administer SW-682 by mouth in 28-day cycles.
Recruiting1 award Phase 16 criteria
SGN-PDL1V
for Cancer
This trial is testing a new drug, SGN-PDL1V, alone and with pembrolizumab, in patients with advanced solid tumors. The goal is to see if these treatments are safe and effective. SGN-PDL1V targets cancer cells directly, while pembrolizumab helps the immune system fight the cancer.
Recruiting1 award Phase 1
More about Afshin Dowlati, MD
Clinical Trial Related1 year of experience running clinical trials · Led 19 trials as a Principal Investigator · 8 Active Clinical TrialsTreatments Afshin Dowlati, MD has experience with
- Carboplatin
- Etoposide
- Nivolumab
- Atezolizumab
- BMS-986012
- RH324
Breakdown of trials Afshin Dowlati, MD has run
Lung Cancer
Non-Small Cell Lung Cancer
Small Cell Lung Cancer
Cancer
Breast Cancer
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