Pedro BARATA | Professor (Associate ...

Dr. Pedro M. Barata

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Tulane University Health Sciences Center

Studies Kidney Cancer
Studies Renal Cell Carcinoma
20 reported clinical trials
52 drugs studied

Area of expertise

1

Kidney Cancer

Pedro M. Barata has run 10 trials for Kidney Cancer. Some of their research focus areas include:

Stage IV
PD-L1 positive
Stage III
2

Renal Cell Carcinoma

Pedro M. Barata has run 9 trials for Renal Cell Carcinoma. Some of their research focus areas include:

Stage IV
Stage III
TFE-3/B translocation positive

Affiliated Hospitals

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Tulane University Health Sciences Center

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Hematology/Oncology Clinic PLLC

Clinical Trials Pedro M. Barata is currently running

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Registry

for Advanced Prostate Cancer

Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingdom (UK), and the United States (US). Target accrual number and number of participating sites are subject to change based on accrual, funding, and interest in participation by other international sites. This cohort study will facilitate a better understanding of the variation in care and treatment of advanced prostate cancer across countries and across academia and community based practices. Detailed data will be collected from patients at study enrollment and then during follow-up, for a minimum of five years. Patients will be followed prospectively for overall survival, clinically significant adverse events, comorbidities, changes in cancer treatments, and PROMs. PROMs questionnaires will be collected at enrollment and every three months thereafter. Physician Questionnaires will be collected from all participating sites at patient enrollment, time of first change in treatment and/or one year follow-up, at each subsequent change of treatment, and discontinuation of treatment. As such, this registry will help identify the treatment sequences or combinations that optimize overall survival and PROMs for men with mHSPC and M0/M1 CRPC. By collecting blood at enrollment, time of first change in treatment and/or one year follow-up (plasma, cell free DNA, buffy coat / RNA), this registry will further identify and validate molecular phenotypes of disease that predict response and resistance to specific therapeutics. Additionally, every effort will be made to collect blood specimen at each subsequent change in treatment due to progression of disease. When feasible, existing tumor tissue may be collected for correlation with described blood based studies. All samples will be used for future research. This cohort study will provide the research community with a unique biorepository to identify biomarkers of treatment response and resistance.

Recruiting

1 award

N/A

5 criteria

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Immunotherapy + Targeted Therapy

for Genitourinary Cancers

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.

Recruiting

1 award

Phase 2

21 criteria

More about Pedro M. Barata

Clinical Trial Related

1 year of experience running clinical trials · Led 20 trials as a Principal Investigator · 6 Active Clinical Trials

Treatments Pedro M. Barata has experience with

  • Nivolumab
  • Ipilimumab
  • Cabozantinib
  • Pembrolizumab
  • Lenvatinib
  • Prednisone

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