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Rainbow Babies and Childrens Hospital
Claim this profileCleveland, Ohio 44106
Global Leader in Cancer
Global Leader in Adult T-Cell Leukemia/Lymphoma
Conducts research for Cystic Fibrosis
Conducts research for Fibrosing Colonopathy
Conducts research for Brain Tumor
356 reported clinical trials
16 medical researchers
Summary
Rainbow Babies and Childrens Hospital is a medical facility located in Cleveland, Ohio. This center is recognized for care of Cancer, Adult T-Cell Leukemia/Lymphoma, Cystic Fibrosis, Fibrosing Colonopathy, Brain Tumor and other specialties. Rainbow Babies and Childrens Hospital is involved with conducting 356 clinical trials across 618 conditions. There are 16 research doctors associated with this hospital, such as Duncan S. Stearns, Michele C Walsh, MD MS, Alex Gifford, MD, and Sanjay Ahuja, MD, MSc, MBA.Area of expertise
1Cancer
Global LeaderStage IV
Stage I
Stage II
2Adult T-Cell Leukemia/Lymphoma
Global LeaderStage II
Stage IV
Stage III
Top PIs
Duncan S. StearnsRainbow Babies and Childrens Hospital8 years of reported clinical research
Expert in Cystic Tumor
Expert in Brain Tumor
57 reported clinical trials
118 drugs studied
Michele C Walsh, MD MSCase Western Reserve University, Rainbow Babies and Children's Hospital6 years of reported clinical research
Studies Low Birth Weight
Studies Small for Gestational Age
6 reported clinical trials
9 drugs studied
Alex Gifford, MDRainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center3 years of reported clinical research
Studies Intestinal Fibrosis
Studies Cystic Fibrosis
6 reported clinical trials
9 drugs studied
Sanjay Ahuja, MD, MSc, MBAUniversity Hospitals Health System Cleveland4 years of reported clinical research
Studies Hemophilia A
Studies Hemophilia B
5 reported clinical trials
6 drugs studied
Clinical Trials running at Rainbow Babies and Childrens Hospital
Brain Tumor
Testicular cancer
Acute Lymphoblastic Leukemia
Cystic Fibrosis
Cancer
Testicular Carcinoma
Adult T-Cell Leukemia/Lymphoma
Germ Cell Tumors
Ovarian Carcinoma
Ovarian Tumors
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Lower Radiotherapy Dose
for Brain Tumors
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.
Recruiting1 award Phase 210 criteria
Chemotherapy + Radiation Therapy
for Brain Cancer
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting1 award Phase 2
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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.