Health Information Collection for Childhood Cancer

Recruiting at 284 trial locations

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Children's Oncology Group

Disqualifiers: Over 25, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

75000 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to collect health information from younger cancer patients to help doctors improve treatments and ongoing care. Participants will provide samples, such as tissue or blood (cytology specimen collection procedure), and their medical data will be reviewed (medical chart review) to create a cancer registry. It is suitable for patients up to 25 years old who have been recently diagnosed with cancer or have experienced a recurrence or progression.

As an unphased study, this trial offers patients the opportunity to contribute to valuable research that may enhance future cancer care.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to create a comprehensive Childhood Cancer Registry, which is a game-changer in understanding and treating childhood cancers. Unlike traditional treatments that focus solely on addressing cancer in the moment, this project collects biospecimen samples and reviews medical data to uncover patterns and insights that could lead to breakthroughs in prevention, diagnosis, and treatment. By gathering detailed biological and medical information from younger patients, this initiative holds the potential to personalize and revolutionize future cancer care for children and adolescents.

Who Is on the Research Team?

Douglas Hawkins

Principal Investigator

Children's Oncology Group

Are You a Good Fit for This Trial?

Inclusion Criteria

Enrollment must occur within 6 months of initial disease presentation OR within 6 months of refractory disease, disease progression, disease recurrence, second or secondary malignancy, or post-mortem

Patients previously enrolled on ACCRN07 are eligible to enroll on Tracking Outcome, Registry and Future Contact components of APEC14B1 any time after they reach age of majority

All cancer cases with an International Classification of Diseases for Oncology (ICD-O) histologic behavior code of two "2" (carcinoma in situ) or three "3" (malignant)

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

Registry and Biospecimen Collection

Patients undergo medical data review to create a Childhood Cancer Registry and collection of biospecimen samples

Follow-up

Participants are monitored for ongoing data collection and potential future research participation

What Are the Treatments Tested in This Trial?

Interventions

• Cytology Specimen Collection Procedure
• Medical Chart Review

How Is the Trial Designed?

Group I: Observational Project: Every Child Protocol Experimental Treatment 2 Interventions

Patients undergo medical data review to create a Childhood Cancer Registry. Patients also undergo collection of biospecimen samples (e.g., tissue, blood, bone marrow, plasma, serum, buccal swab, saliva, cerebrospinal fluid, or urine).

Group II: Observational Project AYA Protocol Experimental Treatment 1 Intervention

Patients undergo collection of biospecimen samples (e.g., tissue, blood, bone marrow, plasma, serum, buccal swab, saliva, cerebrospinal fluid, or urine).

Who Is Running the Clinical Trial?

Children's Oncology Group

Lead Sponsor

Trials

467

Recruited

241,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+