Virtual Reality for Chronic Pain Management

JS
CN
Overseen ByCynthia Nguyen, MPH
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: The Hospital for Sick Children
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether virtual reality (VR) can help teens manage chronic pain more effectively than the usual physical therapy conducted over video calls. The researchers aim to determine if VR use enhances teens' understanding of their treatment, increases their enjoyment, and improves their pain and mobility. The study includes different groups: one using custom VR (a tailored virtual reality program), another using off-the-shelf VR (a commercially available virtual reality system), and a control group continuing with standard virtual physiotherapy. Teens aged 12-18 with chronic pain, attending a specific outpatient clinic, capable of physical activity, and with internet access may be eligible to participate. As an unphased trial, this study provides a unique opportunity for teens to explore innovative pain management techniques and contribute to advancing treatment options.

Do I have to stop taking my current medications for the trial?

The trial requires that you have been on stable medication or therapy for at least one week before starting, meaning no new pain medications or therapies should be introduced during that time.

What prior data suggests that these virtual reality programs are safe for teens with chronic pain?

Research has shown that virtual reality (VR) is generally safe for managing long-term pain. Studies suggest that custom VR treatments can reduce pain and improve quality of life, and they are well-tolerated by both children and adults. Although experts do not fully understand the mechanisms, these treatments appear promising.

For ready-made VR options, research on older adults indicates they are mostly safe. Some individuals have reported minor issues like back pain, but these are uncommon. These VR systems are considered easy to use and integrate well into daily life.

In summary, both custom and ready-made VR treatments are generally safe, with minor risks that are rare and manageable.12345

Why are researchers excited about this trial?

Researchers are excited about using virtual reality (VR) for chronic pain management because it offers an immersive experience that can distract the brain from pain signals. Unlike traditional treatments like medications and physical therapy that focus on directly altering pain pathways or increasing mobility, VR engages users in a virtual environment, potentially reducing pain perception through mental engagement and relaxation. The study tests both custom and off-the-shelf VR programs, which integrate VR sessions with usual care, aiming to enhance the effectiveness and accessibility of pain management options. This innovative approach could provide a non-invasive, drug-free alternative to help individuals manage chronic pain more effectively.

What evidence suggests that virtual reality could be effective for managing chronic pain in teens?

Research shows that virtual reality (VR) can help manage chronic pain. This trial will compare two VR approaches: Custom VR and Off the Shelf VR. Studies have found that special VR programs can greatly reduce pain and improve movement and daily activities. This holds true for both custom-made and store-bought VR systems. Evidence supports VR's positive effects on pain, daily functioning, and quality of life. Although more research is needed, current findings are promising for using VR to help teens with chronic pain.23678

Who Is on the Research Team?

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Jennifer Stinson, RN, PhD

Principal Investigator

The Hospital for Sick Children

Are You a Good Fit for This Trial?

This trial is for teens aged 12-18 with chronic pain, who can speak and read English, are under care at a specific clinic, have stable medication/therapy, can move safely on their own, need at least 4 virtual physiotherapy sessions, and have internet access. It's not for those with seizure risks, major untreated mental illnesses or personality disorders, VR intolerance (like nausea), recent headaches/migraines or concussions.

Inclusion Criteria

My medication for pain has not changed in the last week.
I have been diagnosed with chronic pain.
Willing to have Zoom for Healthcare visits with PT recorded during the study period and, if selected, individual telephone interview with research assistant (RA) audio recorded following the study period
See 5 more

Exclusion Criteria

I have new or worsening headaches, motion sickness, nausea, vomiting, or possible concussion symptoms.
You have a serious untreated mental illness, like depression, anxiety, or PTSD.
You feel very uncomfortable in small spaces or have had a bad experience with virtual reality in the past.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in either a custom VR program or an off-the-shelf VR program combined with standard virtual physiotherapy treatment, or just the standard virtual physiotherapy treatment, over 4 weeks.

4 weeks
1 session per week, total 4 sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment, including assessments of pain intensity, physical functioning, and other outcomes.

1 year

What Are the Treatments Tested in This Trial?

Interventions

  • Custom VR
  • Off the Shelf VR
Trial Overview The study tests if virtual reality programs designed for pain rehabilitation are user-friendly and effective in improving pain management and physical function in teens during COVID-19 compared to standard videoconference physiotherapy. Teens' experiences will be evaluated through questionnaires and interviews.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Active Control
Group I: Off the Shelf VR (PR-VR program + usual care)Experimental Treatment1 Intervention
Group II: Custom VR (Modified PR-VR program + usual care)Experimental Treatment1 Intervention
Group III: Standard Virtual Physiotherapy Treatment (control; usual care),Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

The Hospital for Sick Children

Lead Sponsor

Trials
724
Recruited
6,969,000+

Stanford University

Collaborator

Trials
2,527
Recruited
17,430,000+

Citations

Effectiveness of Virtual Reality for Pain Management in ...VR shows potential for managing pain in MSK disorders, particularly knee conditions, with significant effectiveness using specialised non‐immersive VR.
Virtual reality for pain management: an umbrella reviewThis umbrella review demonstrates successful application of virtual reality in pain control, including perioperative, periprocedural, and chronic pain settings.
Virtual Reality Applications in Chronic Pain ManagementEvidence has been found for the effects of VR on pain, functioning, mobility, functional capacity, psychological outcomes, quality of life, neuropsychological ...
The Role of Virtual Reality in Chronic Pain and LonelinessThis narrative review aims to synthesize current evidence on the effectiveness of VR interventions in managing chronic pain and loneliness, ...
Editorial: Virtual reality for pain managementPreliminary findings suggest potential benefits in reducing pain scores during and after VR combined with SCS, but further research is needed to validate these ...
Virtual Reality Applications in Chronic Pain ManagementEvidence has been found for the effects of VR on pain, functioning, mobility, functional capacity, psychological outcomes, quality of life, neuropsychological ...
Using Virtual Reality Exposure Therapy in Pain ManagementVR is a feasible alternative therapy for both juveniles and adults in pain management, and it has a greater potential for juveniles.
Exploring the use of immersive virtual reality in adults with ...The use of immersive virtual reality for chronic primary pain is in early stages with lack of consensus regarding the mechanisms and associated dose.
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