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Retinoid

Adapinoid vs Retinol for Wrinkles

N/A
Waitlist Available
Research Sponsored by Integrative Skin Science and Research
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Study Summary

This trial looks at how two topical vitamin-A-derived ingredients affect facial skin health, appearance and comfort. One is retinol, the other is Adapinoid.

Who is the study for?
This trial is for men and women aged 35-65 who want to improve their facial skin health and appearance. It's not suitable for prisoners, those unable to consent, recent users of certain cosmetic treatments or products, pregnant/breastfeeding individuals, tobacco smokers with a significant history, or anyone changing hormonal contraception recently.Check my eligibility
What is being tested?
The study compares two vitamin-A derived ingredients: retinol and Adapinoid (Oleyl Adapalenate), applied topically on the face. The goal is to see which one better improves skin health and appearance while checking how well participants tolerate them.See study design
What are the potential side effects?
Potential side effects may include skin irritation, dryness, redness, peeling or sensitivity to sunlight due to the nature of topical vitamin A derivatives used in improving skin conditions.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Facial fine lines and wrinkles
Facial skin pigment evenness
Self-perception of skin health and appearance
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: AdapinoidExperimental Treatment1 Intervention
Product will be used once daily in the evening for 12 weeks. 1-2 pumps (size of quarter) of product will be applied on the face.
Group II: RetinolActive Control1 Intervention
Product will be used once daily in the evening for 12 weeks. 1-2 pumps (size of quarter) of product will be applied on the face.

Find a Location

Who is running the clinical trial?

Integrative Skin Science and ResearchLead Sponsor
31 Previous Clinical Trials
2,684 Total Patients Enrolled
5 Trials studying Wrinkles
195 Patients Enrolled for Wrinkles
ActeraUNKNOWN
1 Previous Clinical Trials
22 Total Patients Enrolled

Media Library

Adapinoid (Retinoid) Clinical Trial Eligibility Overview. Trial Name: NCT05778760 — N/A
Wrinkles Research Study Groups: Adapinoid, Retinol
Wrinkles Clinical Trial 2023: Adapinoid Highlights & Side Effects. Trial Name: NCT05778760 — N/A
Adapinoid (Retinoid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05778760 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are senior citizens being recruited to this trial?

"Patients aged between 35 and 65 are eligible to join this clinical trial."

Answered by AI

To whom is this research opportunity open?

"This clinical trial is recruiting 48 individuals between the ages of 35 and 65 who present visible wrinkles."

Answered by AI

Is this research still open to participants?

"The information housed on clinicaltrials.gov suggests that this experimental trial is not currently seeking volunteers. Initially posted on March 20th, 203 and last revised 10 days later, it has yet to open its recruitment phase; however, 29 other trials are actively enrolling participants at the moment."

Answered by AI
~25 spots leftby Apr 2025