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Diagnostic Test

CT Perfusion for Traumatic Brain Injury (ACT-TBI Trial)

N/A

Waitlist Available

Led By Jai Shankar, MD FRCPC

Research Sponsored by University of Manitoba

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

ACT-TBI Trial Summary

This trial will help to validate if computed tomographic perfusion can diagnose brain death reliably in severe traumatic brain injury patients in the early stage upon hospital admission.

Eligible Conditions

Traumatic Brain Injury

ACT-TBI Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

The is a binary outcome of mortality ('dead') or survival ('not-dead') in the first 48 hours of hospital admission.

Secondary outcome measures

In-hospital mortality at the end of hospital discharge.

ACT-TBI Trial Design

1Treatment groups

Experimental Treatment

Group I: CT PerfusionExperimental Treatment1 Intervention

Severe TBI patients will be undergoing CT perfusion test

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

CT Perfusion

2021

N/A

~300

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Canadian Institutes of Health Research (CIHR)OTHER_GOV

1,344 Previous Clinical Trials

26,453,217 Total Patients Enrolled

University of ManitobaLead Sponsor

595 Previous Clinical Trials

199,322 Total Patients Enrolled

Jai Shankar, MD FRCPCPrincipal InvestigatorUniversity of Manitoba

1 Previous Clinical Trials

91 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In what capacity are local medical centers conducting this experiment?

"This clinical trial currently has 4 active sites, such as the Centre hospitalier de l'Université de Montréal (CHUM) in Montreal and The Ottawa Hospital. Additionally, there are other locations offering this study across Canada, including QEII Health Sciences Center in Halifax."

Answered by AI

How many participants have enrolled in this clinical experiment thus far?

"This trial requires 200 qualified participants, and they can be recruited at two main sites: Centre hospitalier de l'Université de Montréal (CHUM) in Montreal, Quebec or QEII Health Sciences Centre in Halifax, Nova Scotia."

Answered by AI

Are there any vacancies for enrolment in this trial?

"Clinicialtrials.gov has this medical trial listed as currently in search of participants; the posting first went live on July 23rd 2020, with its most recent edit occurring February 3rd 2022."

Answered by AI

Recent research and studies

BMJ OpenJournal

Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI): Protocol for a Prospective Cohort Study

Alcock, Susan, Divjeet Batoo, Sudharsana Rao Ande, Rob Grierson, Marco Essig, Douglas Martin, Anurag Trivedi, et al.. 2021. “Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI): Protocol for a Prospective Cohort Study”. BMJ Open. BMJ. doi:10.1136/bmjopen-2020-047305.

clinicaltrials.govStudy

Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study)

Jai Shankar 2020. "Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04318665.