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Discontinuing CRRT for Acute Kidney Injury (DC-CRRT Trial)

N/A
Recruiting
Led By Khaled Shawwa, MD
Research Sponsored by West Virginia University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Being started on continuous renal replacement therapy
Diagnosis of acute kidney injury
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 to 100 days
Awards & highlights

DC-CRRT Trial Summary

This trial will look at whether a new approach to ending CRRT in AKI patients, based on evidence, improves outcomes compared to usual care.

Who is the study for?
This trial is for patients with acute kidney injury who are currently on Continuous Renal Replacement Therapy (CRRT). It's not open to those with chronic kidney disease stage 5, end-stage renal disease, recent RRT treatment, or certain severe conditions like intoxication needing extracorporeal removal.Check my eligibility
What is being tested?
The study tests if using specific criteria to stop CRRT can improve patient outcomes. Participants will be split into two groups: one follows usual care and the other uses these new guidelines based on factors like urine output and hemodynamic status.See study design
What are the potential side effects?
Since this trial involves discontinuing a treatment rather than administering a drug, side effects may include potential complications related to kidney function recovery such as fluid imbalance or changes in electrolyte levels.

DC-CRRT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am starting treatment for my kidneys with a machine.
Select...
I have been diagnosed with acute kidney injury.

DC-CRRT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 to 100 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 to 100 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Successful discontinuation of Continuous Renal Replacement Therapy
Secondary outcome measures
Adverse events occurring within 7 days after discontinuation of CRRT
CRRT duration
Intermittent hemodialysis after CRRT discontinuation
+1 more

DC-CRRT Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Standardized approach to discontinuation of CRRTExperimental Treatment1 Intervention
Criteria-driven approach
Group II: Usual Process of CareActive Control1 Intervention
No intervention

Find a Location

Who is running the clinical trial?

West Virginia UniversityLead Sponsor
176 Previous Clinical Trials
60,072 Total Patients Enrolled
1 Trials studying Acute Kidney Injury
3 Patients Enrolled for Acute Kidney Injury
Khaled Shawwa, MDPrincipal InvestigatorWest Virginia University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Discontinuing CRRT in Patients With Acute Kidney Injury
Khaled Shawwa 2021. "Discontinuing CRRT in Patients With Acute Kidney Injury". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04898595.
~0 spots leftby May 2024
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