Study Summary
This trial will test if ketamine can help reduce the amount of opioids needed for pain relief in adults with severe injuries.
- Hospital Inpatient Trauma Injury
- Pain Management
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 0 Secondary · Reporting Duration: The first 24 hours
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
Ketamine arm
1 of 2
Placebo arm
1 of 2
Experimental Treatment
Non-Treatment Group
130 Total Participants · 2 Treatment Groups
Primary Treatment: Ketamine · Has Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 64 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Bertolini F, Robertson L, Bisson JI, Meader N, Churchill R, Ostuzzi G, Stein DJ, Williams T, Barbui C. Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD). Cochrane Database Syst Rev. 2022 Feb 10;2:CD013443. doi: 10.1002/14651858.CD013443.pub2. Review.
- Bertolini F, Robertson L, Bisson JI, Meader N, Churchill R, Ostuzzi G, Stein DJ, Williams T, Barbui C. Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD). Cochrane Database Syst Rev. 2022 Feb 10;2(2):CD013443. doi: 10.1002/14651858.CD013443.pub2.
- Thomas Carver 2021. "Ketamine for Pain Control After Severe Traumatic Injury". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04274361.
Frequently Asked Questions
Is the trial currently open to new participants?
"Clinicaltrials.gov states that this research is recruiting participants and has been active since its initial posting on April 1st 2021, with the latest edit taking place on December 1st 2021." - Anonymous Online Contributor
Does the trial accept participants aged seventy or above?
"This clinical trial is recruiting patients that are older than 18 years but younger than 64." - Anonymous Online Contributor
Is it feasible for me to apply to this clinical experiment?
"This medical investigation is enrolling 130 individuals with pain management issues that are between 18 and 64 years old. Essential requirements include: being within 12 hours of FMLH at the time of recruitment, inpatient hospital admission to trauma services, an ISS score higher than 15 points, and no immediate plans for OR treatment." - Anonymous Online Contributor
What is the enrollment capacity of this medical research project?
"Affirmative. According to the records hosted on clinicaltrials.gov, this medical experiment is currently recruiting participants as of December 1st 2021. It was originally posted on April 4th 2021 and requires 130 patients from a single site." - Anonymous Online Contributor