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transcranial Random Noise Stimulation (tRNS) for Quadriplegia

N/A
Waitlist Available
Led By Anastasia Zarkou, PT,MS,PhD
Research Sponsored by Shepherd Center, Atlanta GA
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline; post testing week 1; post testing week 2
Awards & highlights

Study Summary

This study is evaluating whether a combination of brain stimulation and physical therapy may help improve hand function for individuals with spinal cord injury.

Eligible Conditions
  • Quadriplegia
  • Spinal Cord Injury

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline; post testing week 1; post testing week 2
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline; post testing week 1; post testing week 2 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Cortical excitability
Change in Sensory function (sensation subtest of the Graded Redefined Assessment of Strength Sensibility and Prehension)
Change in Strength (key pinch and grasp strength)
Secondary outcome measures
Change in Bimanual function (Chedoke Arm and Hand Activity Inventory)
Change in Sensory Function (revised Nottingham Sensory Assessment)
Body Weight Changes

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: transcranial Random Noise Stimulation (tRNS)Experimental Treatment2 Interventions
Participants in this group will receive a combined intervention (3 days of tRNS during functional task practice and 3 days of sham-stimulation during functional task practice).
Group II: transcranial Direct Current Stimulation (tDCS)Active Control2 Interventions
Participants in this group will receive a combined intervention (3 days of tDCS during functional task practice and 3 days of sham-stimulation during functional task practice).

Find a Location

Who is running the clinical trial?

Shepherd Center, Atlanta GALead Sponsor
28 Previous Clinical Trials
3,632 Total Patients Enrolled
7 Trials studying Quadriplegia
241 Patients Enrolled for Quadriplegia
The Craig H. Neilsen FoundationOTHER
55 Previous Clinical Trials
2,916 Total Patients Enrolled
3 Trials studying Quadriplegia
85 Patients Enrolled for Quadriplegia
Anastasia Zarkou, PT,MS,PhDPrincipal InvestigatorShepherd Center, Atlanta GA

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function
2021. "Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04777149.
~5 spots leftby Apr 2025
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