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Intramuscular Stimulation for Whiplash

N/A
Waitlist Available
Led By Brenda Lau, MD
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 6 months after 12-week treatment is complete
Awards & highlights

Study Summary

This pilot study is being conducted to provide proof of concept for three recently developed needling treatments, in the treatment of whiplash associated disorder type 2 (WAD-II). The investigators aim to show that these techniques should be considered as regular, effective options for people suffering from WAD-II. These techniques are Intramuscular stimulation (IMS), neural prolotherapy (NPT), and myoActivation (mA). Additionally, the investigators plan to begin profiling responders and non-responders in an effort to identify which treatment is likely to work best for different people. In the future, this may help to expedite treatment for WAD-II, helping patients get the most appropriate treatment, more quickly. The investigators expect to show that all three treatments are significantly better than a placebo treatment, and to collect information on what makes each technique more or less likely to work for individual cases.

Eligible Conditions
  • Whiplash

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 6 months after 12-week treatment is complete
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6 months after 12-week treatment is complete for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from baseline in Brief Pain Inventory - Short Form at 6 months post-treatment
Secondary outcome measures
Anxiety Disorders
Change in Depression as measured by the 9-item Patient Health Questionnaire (PHQ-9) 6 months post-treatment
Change in Neck Disability Index at 6-months post treatment
+2 more

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: myoActivationExperimental Treatment1 Intervention
Participants in this group will receive up to 12 sessions of myoActivation treatment. Each treatment is approximately 15 minutes. Primary and Secondary outcome measures will be assessed prior to treatment, one week after all treatments have been completed, and again 6 months after treatment is complete.
Group II: Neural ProlotherapyExperimental Treatment1 Intervention
Participants in this group will receive up to 12 sessions of neural prolotherapy. treatment. Each treatment is approximately 30 to 60 minutes minutes. Primary and Secondary outcome measures will be assessed prior to treatment, one week after all treatments have been completed, and again 6 months after treatment is complete.
Group III: Intramuscular StimulationExperimental Treatment1 Intervention
Participants in this group will receive up to 12 sessions of Intramuscular Stimulation (IMS). Each session may last from 30 to 60 minutes. Primary and secondary outcome measures will be assessed prior to the first treatment, after completion of the last treatment, and 6 months after treatment is complete.
Group IV: Sham Needling ControlPlacebo Group1 Intervention
Participants in this group will receive up to 12 sessions of sham needle treatment. Each treatment is approximately 15 to 60 minutes. Primary and Secondary outcome measures will be assessed prior to treatment, one week after all treatments have been completed, and again 6 months after treatment is complete.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
myoActivation
2020
N/A
~50

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor
1,415 Previous Clinical Trials
2,466,984 Total Patients Enrolled
Brenda Lau, MDPrincipal InvestigatorUniversity of British Columbia
Krista B Friesen, MScStudy DirectorUniversity of British Columbia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~3 spots leftby Apr 2025