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Behavioural Intervention

Sequence 1 for Obesity

N/A

Recruiting

Led By Dale Bond, PhD

Research Sponsored by Hartford Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be 18-60 years of age

Seeking to undergo primary (not revisional) bariatric surgery at HH

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the rrv score will be obtained immediately before and immediately after the rtms and immediately before and after the sham tms

Awards & highlights

Study Summary

This trial will explore if rTMS can reduce the reinforcing value of food and related reward processes in people who find food highly rewarding, compared to an alternative reinforcer.

Who is the study for?

This trial is for adults aged 18-60 who are planning to have bariatric surgery, can consent in English, and typically eat breakfast before 8 AM. They should not have cognitive impairments or ADHD, with an IQ of at least 80. Participants must also exhibit high levels of pleasure-driven eating and overeating susceptibility but meet safety standards for EEG and rTMS procedures.Check my eligibility

What is being tested?

The study tests if transcranial magnetic stimulation (rTMS) can reduce the desire to eat for pleasure rather than hunger among preoperative bariatric patients. It involves two sessions: one with real rTMS and another with sham (fake) treatment, both targeting the brain's reward centers while measuring food reinforcement value against money.See study design

What are the potential side effects?

While side effects are not detailed here, typical ones from rTMS may include headache, scalp discomfort at the site of stimulation, tingling or spasms in facial muscles, lightheadedness, or seizures (very rare).

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 18 and 60 years old.

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I am planning to have my first weight loss surgery at HH.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the rrv score will be obtained immediately before and immediately after the rtms and immediately before and after the sham tms

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the rrv score will be obtained immediately before and immediately after the rtms and immediately before and after the sham tms

This trial's timeline: 3 weeks for screening, Varies for treatment, and the rrv score will be obtained immediately before and immediately after the rtms and immediately before and after the sham tms for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in scores on the Relative-Reinforcing Value (RRV) of Food Questionnaire

Trial Design

2Treatment groups

Experimental Treatment

Group I: Sequence 2Experimental Treatment1 Intervention

Sham TMS followed by TMS

Group II: Sequence 1Experimental Treatment1 Intervention

TMS followed by sham TMS

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Hartford HospitalLead Sponsor

133 Previous Clinical Trials

18,920 Total Patients Enrolled

5 Trials studying Obesity

433 Patients Enrolled for Obesity

Dale Bond, PhDPrincipal InvestigatorHartford HealthCare

1 Previous Clinical Trials

32 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment process currently in progress for participants of this research study?

"According to clinicaltrials.gov, this investigation is presently enrolling participants. The trial was initially posted on January 26th, 2023 and the most recent update was made on December 5th, 2023."

Answered by AI

What is the upper limit for the number of participants involved in this research endeavor?

"Indeed, the details available on clinicaltrials.gov indicate that this research is actively seeking participants. The trial was initially listed on January 26, 2023, and its most recent update was made on December 5, 2023. Specifically, it aims to enroll a total of 12 subjects at one designated site."

Answered by AI

Are individuals older than 30 years eligible to participate in this medical research study?

"Eligible candidates for this research study must fall within the age bracket of 18 to 60 years. Notably, there are a total of 178 trials catering to individuals under 18 and 628 focusing on those over 65 years old."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Can Transcranial Magnetic Stimulation Decrease Food Reinforcement

2023. "Can Transcranial Magnetic Stimulation Decrease Food Reinforcement". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05522803.

All > Transcranial Magnetic Stimulation