Charge for Obesity

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Obesity+1 MoreCharge - Behavioral
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test different versions of a weight-loss app that uses text messaging. It will enroll 448 adults and follow them for 6 months, with a 6-month follow-up.

Eligible Conditions
  • Obesity
  • Weight Loss

Treatment Effectiveness

Study Objectives

1 Primary · 6 Secondary · Reporting Duration: baseline, 6 & 12 months

baseline & 6 months
Compare Cost-effectiveness of interventions
Weight
Month 12
Change in categorical weight loss (> 5%) at 6-months
Change in diet
Change in physical activity
Measure engagement in the intervention
weight loss maintenance

Trial Safety

Trial Design

32 Treatment Groups

Arm 3: WT-SM-OR-SF-CS
1 of 32
Arm 32: DT-EM-MR-GF-CG
1 of 32
Arm 2: WT-SM-OR-SS-CG
1 of 32
Arm 10: WT-EM-OR-SS-CG
1 of 32
Arm 4: WT-SM-OR-SF-CG
1 of 32
Arm 5: WT-SM-MR-SS-CS
1 of 32
Arm 13: WT-EM-MR-SS-CS
1 of 32
Arm 9: WT-EM-OR-SS-CS
1 of 32
Arm 14: WT-EM-MR-SS-CG
1 of 32
Arm 15: WT-EM-MR-SF-CS
1 of 32
Arm 31: DT-EM-MR-GF-CS
1 of 32
Arm 1: WT-SM-OR-SS-CS
1 of 32
Arm 8: WT-SM-MR-SF-CG
1 of 32
Arm 16: WT-EM-MR-SF-CG
1 of 32
Arm 7: WT-SM-MR-SF-CS
1 of 32
Arm 11: WT-EM-OR-SF-CS
1 of 32
Arm 12: WT-EM-OR-SF-CG
1 of 32
Arm 6: WT-SM-MR-SS-CG
1 of 32
Arm 17: DT-SM-OR-SS-CS
1 of 32
Arm 19: DT-SM-OR-SF-CS
1 of 32
Arm 20: DT-SM-OR-SF-CG
1 of 32
Arm 18: DT-SM-OR-SS-CG
1 of 32
Arm 21: DT-SM-MR-SS-CS
1 of 32
Arm 22: DT-SM-MR-SS-CG
1 of 32
Arm 25: DT-EM-OR-SS-CS
1 of 32
Arm 27: DT-EM-OR-SF-CS
1 of 32
Arm 30: DT-EM-MR-SS-CG
1 of 32
Arm 23: DT-SM-MR-SF-CS
1 of 32
Arm 24: DT-SM-MR-SF-CG
1 of 32
Arm 26: DT-EM-OR-SS-CG
1 of 32
Arm 28: DT-EM-OR-SF-CG
1 of 32
Arm 29: DT-EM-MR-SS-CS
1 of 32

Experimental Treatment

448 Total Participants · 32 Treatment Groups

Primary Treatment: Charge · No Placebo Group · N/A

Arm 3: WT-SM-OR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 32: DT-EM-MR-GF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 2: WT-SM-OR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 10: WT-EM-OR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 4: WT-SM-OR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 5: WT-SM-MR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 13: WT-EM-MR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 9: WT-EM-OR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 14: WT-EM-MR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 15: WT-EM-MR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 31: DT-EM-MR-GF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 1: WT-SM-OR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 8: WT-SM-MR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 16: WT-EM-MR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 7: WT-SM-MR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 11: WT-EM-OR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 12: WT-EM-OR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 6: WT-SM-MR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 17: DT-SM-OR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 19: DT-SM-OR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 20: DT-SM-OR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 18: DT-SM-OR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 21: DT-SM-MR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 22: DT-SM-MR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 25: DT-EM-OR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 27: DT-EM-OR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 30: DT-EM-MR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 23: DT-SM-MR-SF-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 24: DT-SM-MR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 26: DT-EM-OR-SS-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 28: DT-EM-OR-SF-CG
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral
Arm 29: DT-EM-MR-SS-CS
Behavioral
Experimental Group · 1 Intervention: Charge · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 6 & 12 months

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,185 Previous Clinical Trials
3,210,788 Total Patients Enrolled
75 Trials studying Obesity
30,962 Patients Enrolled for Obesity
Gary G Bennett, PhDPrincipal InvestigatorBishop-MacDermott Family Professor of Psychology, Global Health & Medicine
5 Previous Clinical Trials
982 Total Patients Enrolled
3 Trials studying Obesity
628 Patients Enrolled for Obesity

Eligibility Criteria

Age 18 - 65 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Who else is applying?

What state do they live in?
North Carolina33.3%
Oregon33.3%
South Carolina33.3%
How old are they?
18 - 65100.0%
What site did they apply to?
Duke University100.0%
What portion of applicants met pre-screening criteria?
Met criteria66.7%
Did not meet criteria33.3%
References