← Back to Search

Vitamin Supplement

Intervention for Vitamin D Deficiency

N/A
Waitlist Available
Led By Raewyn Broady, MBChB
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This study is to assess whether a single oral loading dose of 100,000 IU vitamin D3 prior to allogeneic hematopoietic stem cell transplant (aHSCT) can achieve optimal 25 hydroxy-vitamin D3(25-OH-D3) levels (>75nmol/L) at one month post aHSCT, and maintain adequate levels for at least three months, compared to our standard practice of 2000 IU vitamin D3 daily. 25-OH-D3 levels will be measured prior to vitamin D3 supplementation, and 30 as well as 100 days post vitamin D supplementation. We hypothesize that the intervention will prevent vitamin D insufficiency or deficiency in aHSCT recipients, therefore benefit aHSCT-associated morbidity, including osteoporosis.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To assess the efficacy of 100,000 IU vitamin D3 prior to aHSCT

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
Participants assigned to the intervention group will receive a single oral loading dose of 100,000 IU vitamin D3 on the day of hospital admission for aHSCT, with subsequent vitamin D3 2000 IU daily.
Group II: ControlActive Control1 Intervention
Participants assigned to the control group will be advised to take our current vitamin D regimen (2000 IU vitamin D3 daily).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
vitamin D3
2010
Completed Phase 4
~4400

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor
1,415 Previous Clinical Trials
2,466,932 Total Patients Enrolled
2 Trials studying Vitamin D Deficiency
312 Patients Enrolled for Vitamin D Deficiency
Raewyn Broady, MBChBPrincipal InvestigatorBritish Columbia Cancer Agency
1 Previous Clinical Trials
20 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Vitamin D3 Supplementation for AlloHSCT-RCT
Raewyn Broady 2018. "Vitamin D3 Supplementation for AlloHSCT-RCT". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03534674.
All > Vitamin D
~12 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top