Alcohol Abstinence Intervention for Alcohol Drinking

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Texas at Arlington, Arlington, TX
Alcohol Drinking+9 More
Alcohol Abstinence Intervention - Behavioral
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers. Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers

Eligible Conditions

  • Aging
  • Alcohol Drinking
  • Alcohol Abstinence
  • Vasodilation
  • Lifestyle Factors
  • Binge Drinking
  • Behavioural Problem
  • Blood Pressures

Treatment Effectiveness

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: Through out the study participation (~3 months)

Baseline and after an 8-week intervention
Changes in alcohol intake
Changes in blood pressure
Changes in microvascular function
Changes in sympathetic activity
Changes in urine catecholamine levels
Month 3
Feasibility of high-intensity interval training

Trial Safety

Trial Design

3 Treatment Groups

Non-exercise Group
1 of 3
Alcohol abstainer/moderate drinker group
1 of 3
Exercise Group
1 of 3
Active Control
Experimental Treatment

55 Total Participants · 3 Treatment Groups

Primary Treatment: Alcohol Abstinence Intervention · No Placebo Group · N/A

Exercise GroupExperimental Group · 2 Interventions: Alcohol Abstinence Intervention, Exercise Training · Intervention Types: Behavioral, Behavioral
Non-exercise Group
Behavioral
ActiveComparator Group · 1 Intervention: Alcohol Abstinence Intervention · Intervention Types: Behavioral
Alcohol abstainer/moderate drinker groupNoIntervention Group · 1 Intervention: Alcohol abstainer/moderate drinker group · Intervention Types:
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exercise Training
2011
Completed Phase 3
~1430

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: through out the study participation (~3 months)
Closest Location: University of Texas at Arlington · Arlington, TX
Photo of texas 1Photo of texas 2Photo of texas 3
2019First Recorded Clinical Trial
1 TrialsResearching Alcohol Drinking
1 CompletedClinical Trials

Who is running the clinical trial?

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
692 Previous Clinical Trials
1,168,054 Total Patients Enrolled
226 Trials studying Alcohol Drinking
74,390 Patients Enrolled for Alcohol Drinking
The University of Texas at ArlingtonLead Sponsor
24 Previous Clinical Trials
2,598 Total Patients Enrolled
Chueh-Lung Hwang, PhDPrincipal InvestigatorUniversity of Texas at Arlington

Eligibility Criteria

Age 18 - 65 · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
Female subjects will be postmenopausal (i.e., cessation of menses for ≥1 yr).
You can speak and understand English.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.