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18-FDG PET/CT, DWI, DCE-MRI for Cervical Carcinoma
N/A
Waitlist Available
Led By Kathy Han, MD
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
Study Summary
This trial is investigating whether using different types of imaging to plan brachytherapy for cervix cancer results in better tumor visualization, which may improve the effectiveness of the treatment.
Eligible Conditions
- Cervical Carcinoma
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Target delineation in brachytherapy using standard T2-weighted MRI versus DCE-MRI, DWI and FDG-PET/CT imaging: gross tumor volume and high-risk clinical target volume in patients with cervical cancer
Target delineation using standard MRI acquired during the last week of EBRT fused to planning CT versus full MRI-guided brachytherapy.
Secondary outcome measures
Follow-up imaging (MRI and 18FDG PET) versus the imaging done at the time of brachytherapy
Imaging techniques for visualizing the brachytherapy applicator.
Trial Design
1Treatment groups
Experimental Treatment
Group I: 18-FDG PET/CT, DWI, DCE-MRIExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
18-FDG PET/CT, DWI, DCE-MRI
2012
N/A
~30
Find a Location
Who is running the clinical trial?
University Health Network, TorontoLead Sponsor
1,466 Previous Clinical Trials
484,330 Total Patients Enrolled
Princess Margaret Hospital, CanadaOTHER
118 Previous Clinical Trials
38,658 Total Patients Enrolled
1 Trials studying Cervical Carcinoma
90 Patients Enrolled for Cervical Carcinoma
Kathy Han, MDPrincipal InvestigatorUniversity Health Network, The Princess Margaret
2 Previous Clinical Trials
155 Total Patients Enrolled
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