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Dextrose + Washout versus Normal Saline for Urinary Tract Infection

N/A

Waitlist Available

Led By Jeffrey Cornella, MD

Research Sponsored by Mayo Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6-9 days post-operative

Awards & highlights

Study Summary

This trial will compare UTI rates in patients who had hysterectomy with two different bladder washout solutions. Results will measure UTI rates 6-9 days after surgery.

Who is the study for?

This trial is for patients scheduled for hysterectomy without a history of diabetes, chronic kidney disease, or recurrent UTIs. It excludes those with ureteral injury, chronic immunosuppression, renal anomalies, and anyone who needs an indwelling catheter for more than 24 hours post-surgery.Check my eligibility

What is being tested?

The study compares the effectiveness of using 50% dextrose injection plus bladder washout versus normal saline in preventing urinary tract infections after a hysterectomy. The main focus is on the number of UTIs occurring within 6-9 days post-operation.See study design

What are the potential side effects?

Potential side effects may include discomfort from the cystoscopy fluid used during surgery. Specific side effects related to the use of dextrose or saline will be monitored and compared between groups.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6-9 days post-operative

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6-9 days post-operative

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6-9 days post-operative for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

rates of urinary tract infections at 6-9 days post-operative

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: 50% dextroseActive Control1 Intervention

Cystoscopic distention of 40 cc of 50% dextrose plus 300 cc of normal saline washout

Group II: Normal SalinePlacebo Group1 Intervention

Cystoscopic distention media of normal saline.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor

3,216 Previous Clinical Trials

3,767,348 Total Patients Enrolled

3 Trials studying Hysterectomy

170 Patients Enrolled for Hysterectomy

Jeffrey Cornella, MDPrincipal InvestigatorMayo Clinic

1 Previous Clinical Trials

4 Total Patients Enrolled

Johnny Yi, MDPrincipal InvestigatorMayo Clinic

2 Previous Clinical Trials

30 Total Patients Enrolled

Media Library

50% dextrose Clinical Trial Eligibility Overview. Trial Name: NCT03719755 — N/A

Hysterectomy Research Study Groups: 50% dextrose, Normal Saline

Hysterectomy Clinical Trial 2023: 50% dextrose Highlights & Side Effects. Trial Name: NCT03719755 — N/A

50% dextrose 2023 Treatment Timeline for Medical Study. Trial Name: NCT03719755 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants able to join this medical experiment currently?

"Affirmative. Per the clinicaltrials.gov portal, this medical experiment has been recruiting since February 1st 2018 and was most recently updated on April 19th 2023. The trial is seeking to enroll 140 participants from a single research centre."

Answered by AI

How many individuals are eligible for inclusion in this clinical research?

"Affirmative. According to clinicaltrials.gov, this study is enrolled recruitments at the present time. It was first made available on February 1st 2018 and its most recent update happened on April 19th 2023. In total, 140 patients are required at a single site of recruitment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid

Johnny Yi 2018. "Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03719755.

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