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3 Tesla MRI for Bladder Cancer

N/A
Waitlist Available
Led By Michael V. Knopp, MD, PhD
Research Sponsored by University of Cincinnati
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Scheduled for radical cystectomy and lymph node dissection
Known bladder cancer
Must not have
Patient with significant renal insufficiency, i.e. an estimated glomerular filtration rate (eGFR) less than 30 mL/min/1.73m2
Patients with sickle cell anemia and other hemolytic anemia
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 24 months
Awards & highlights

Summary

This trial is studying how well a 3 Tesla MRI works in finding cancer in patients with bladder cancer.

Who is the study for?
This trial is for individuals with confirmed bladder cancer who are scheduled for surgery to remove the bladder and lymph nodes. Participants must be able to consent and have no issues that would prevent them from undergoing an MRI, such as allergies to contrast agents or severe kidney problems.Check my eligibility
What is being tested?
The study is evaluating how effective a high-powered 3 Tesla MRI is in detecting bladder cancer compared to standard approaches. Patients will undergo this advanced imaging before their planned surgeries.See study design
What are the potential side effects?
While MRIs don't typically cause side effects, some patients may experience discomfort or anxiety due to the enclosed space of the machine (claustrophobia) or reactions to contrast agents used during the procedure.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am scheduled for surgery to remove my bladder and nearby lymph nodes.
Select...
I have been diagnosed with bladder cancer.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
My kidney function is significantly reduced.
Select...
I have sickle cell anemia or another type of hemolytic anemia.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Agreement in tumor staging between pathology and 3 Tesla MRI
Secondary outcome measures
Agreement in lymph node staging between pathology and 3 Tesla MRI

Trial Design

2Treatment groups
Experimental Treatment
Group I: MRI+surgery+chemotherapyExperimental Treatment3 Interventions
3 Tesla MRI/Cystectomy and Lymphadenectomy/Urinary Diversion/Specimen Ultra-High field MRI/chemotherapy
Group II: MRI+surgeryExperimental Treatment2 Interventions
3 Tesla MRI/Cystectomy and Lymphadenectomy/Urinary Diversion/Specimen Ultra-High field MRI
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
chemotherapy
2002
Completed Phase 3
~2660

Find a Location

Who is running the clinical trial?

University of CincinnatiLead Sponsor
431 Previous Clinical Trials
634,448 Total Patients Enrolled
Ohio State University Comprehensive Cancer CenterLead Sponsor
325 Previous Clinical Trials
290,506 Total Patients Enrolled
Michael V. Knopp, MD, PhDPrincipal Investigator - Ohio State University Comprehensive Cancer Center
Ohio State University Comprehensive Cancer Center
~3 spots leftby Dec 2024