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Sulforaphane for Fragile X Syndrome
Study Summary
This trial is testing a dietary supplement called Sulforaphane to see if it affects specific biomolecular markers captured in blood. Participants take increasing doses of the supplement over 6 months and have 3 medical evaluations.
- Fragile X Associated Tremor/Ataxia Syndrome (FXTAS)
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2013 Phase 2 trial • 20 Patients • NCT01228084Trial Design
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Frequently Asked Questions
What is the current enrollment tally for participants in this trial?
"Affirmative. According to the clinicaltrials.gov database, this trial is currently searching for suitable participants. This research was initially posted on June 25th 2021 and has been revised as recently as January 31st 2022. The researchers are looking to recruit 15 individuals from one specific site."
What are the primary goals of this research initiative?
"The principal objective of this medical trial, tracked across Baseline and 6 months, is to ascertain any fluctuations in mitochondrial function through the production of Adenosine Triphosphate (ATP). Other secondary outcomes being measured include changes in kinetic, postural and rest tremor upper extremity bradykinesia/hypokinesia/dysrhythmia/dyskinesias as quantified by pre-ordained Kinesia One tests; alterations in Fragile X Tremor Ataxia Syndrome (FXTAS) clinical staging via a standardised neurological examination;; plus shifts occurring within subcortical brain"
Is the elderly population allowed to partake in this experiment?
"The age range for acceptance into this trial is between 50 and 85 years old."
Are there any vacancies available within this research project?
"Affirmative. Clinicaltrials.gov's records demonstrate that this clinical trial is presently recruiting participants, having been first publicized on June 25th 2021 and most recently amended on January 31st 2022. The investigators are seeking 15 patients from one site to take part in the study."
May I partake in this research endeavor?
"This research study seeks to recruit 15 individuals with ataxia in the ages of 50-85. All applicants should satisfy two key considerations: A diagnosis of FXTAS and a FMR1 premutation (55 to 200 CGG repeats)."
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