E-cigarette Cessation for Vaping Teens

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Florida International University

Disqualifiers: Severe psychiatric conditions, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 9

Duration: 6 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help Hispanic/Latino high school students quit using e-cigarettes. Researchers will create a program called the E-cigarette Cessation Manual to support these teens in reducing their vaping habits. The program's effectiveness will be tested with 120 students who have used e-cigarettes in the past month. High school students who identify as Hispanic/Latino and currently use e-cigarettes may be a good fit for this trial. As an unphased study, this trial offers a unique opportunity for students to contribute to developing a program that could help many others quit vaping.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It might be best to discuss this with the trial coordinators.

What prior data suggests that this e-cigarette cessation intervention is safe for Hispanic/Latino high school students?

Research has shown that programs designed to help teens stop vaping can be effective. These programs increase the number of participants who quit using e-cigarettes for at least a week, and sometimes even for a year. However, e-cigarettes might not assist teens in quitting regular cigarettes. In fact, starting with e-cigarettes can sometimes lead to smoking regular cigarettes later.

For safety, the trial employs a guide to help teens quit e-cigarettes. No physical treatments or medications are involved, which typically results in fewer safety concerns. The focus is on changing behavior, making the program quite safe since it doesn't involve taking any new drugs. The goal is to help reduce e-cigarette use, which is important because nicotine can affect learning and memory in young people. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the E-cigarette Cessation Manual because it offers a fresh approach to help teens quit vaping, focusing on behavioral change rather than medication or nicotine replacement therapies like patches or gums. This manual provides structured guidance and strategies specifically tailored for young people, addressing the psychological and social aspects of vaping that are often overlooked by existing treatments. By empowering teens with practical tools and support, this method aims to reduce dependence on e-cigarettes more effectively and in a way that resonates with their unique experiences and challenges.

What evidence suggests that this e-cigarette cessation manual is effective for reducing vaping in teens?

Research has shown that programs to help people stop vaping can be effective. For example, a personalized text message program helped more teens quit e-cigarettes. Another study found that a phone support service helped nearly half of young adults stop vaping after three months. Overall, different methods have successfully increased short-term quitting rates. These findings suggest that targeted programs can effectively reduce e-cigarette use among teens. ^{2 5 6 7 8}

Are You a Good Fit for This Trial?

This trial is for Hispanic/Latino high school students in Florida who use e-cigarettes and want to quit. It's designed specifically to help this group, taking into account their unique cultural and social needs.

Inclusion Criteria

Identify as being of Hispanic/Latino origin

Report past month e-cigarette use and verified by saliva cotinine test

I am between 14 and 18 years old or currently enrolled in high school.

Exclusion Criteria

History of severe psychiatric conditions (e.g., bipolar disorder)

Currently enrolled in or planning on enrolling in another e-cigarette and/or tobacco cessation intervention

Potential difficulties comprehending study procedures (e.g., not able to speak/write in English or Spanish, have a severe learning disability)

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

1 visit (in-person)

Preparation to Quit

Participants attend a session to prepare for quitting, including setting a quit day and making a quit plan

1 week

1 visit (in-person)

Treatment

Participants undergo a 6-week Cognitive Behavioral Therapy intervention with weekly sessions to aid in e-cigarette cessation

6 weeks

6 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including a follow-up questionnaire and salivary cotinine assessment

3 months

1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

• E-cigarette Cessation Manual

Trial Overview The study is testing a new manual-based intervention aimed at helping these teens stop using e-cigarettes. The program will be shaped by feedback from the students themselves and a community advisory board.

How Is the Trial Designed?

Group I: Single Arm Experimental Treatment 1 Intervention

See Intervention Section

Who Is Running the Clinical Trial?

Florida International University

Lead Sponsor

Trials

114

Recruited

19,400+

James and Esther King Biomedical Research Program

Collaborator

Trials

15

Recruited

2,200+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10995917/

Adoption of Vaping Cessation Methods by US Adolescent ... A large number of adolescent e-cigarette users intend to quit vaping or have past-year quit attempts. However, it remains unknown which methods they use in ...

2. jamanetwork.com jamanetwork.com/journals/jama/fullarticle/2822082

A Vaping Cessation Text Message Program for Adolescent ... A tailored, interactive text message intervention increased self-reported vaping cessation rates among adolescents recruited via social media channels.

3. ajpmonline.org ajpmonline.org/article/S0749-3797(24)00371-4/fulltext

Quitline-Based Young Adult Vaping Cessation This quitline-delivered intervention was successful at helping young adults quit vaping, with almost half abstinent after 3 months.

4. tobaccocontrol.bmj.com tobaccocontrol.bmj.com/content/early/2025/02/20/tc-2024-058798

Vaping cessation interventions: a systematic review and ... Vaping cessation interventions increase 7-day PPA rates at 1–12 months follow-up and this was consistent across prespecified subgroup analyses.

5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC8129897/

Effectiveness of a Vaping Cessation Text Message ... This randomized clinical trial determines the effectiveness of a text message program for vaping cessation among young adults aged 18 to 24 years vs assessment ...

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC9663538/

E-cigarettes and smoking cessation among adolescent ... Our findings suggest that e-cigarettes may not aid tobacco control among adolescent smokers. Policy makers should be cautious of the potential harms.

7. publications.aap.org publications.aap.org/pediatrics/article/151/5/e2023061805/191063/Protecting-Children-and-Adolescents-From-Tobacco

Protecting Children and Adolescents From Tobacco and ... Significant strides have been made in reducing rates of cigarette smoking among adolescents in the United States.

8. ajpmonline.org ajpmonline.org/article/S0749-3797(23)00389-6/fulltext

Interventions for Preventing E-Cigarette Use Among ... Association between initial use of e-cigarettes and subsequent cigarette smoking among adolescents and young adults: a systematic review and meta-analysis