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Nicotine Replacement Therapy

Dual nicotine patch and electronic cigarette for Nicotine Addiction

N/A

Recruiting

Led By Amy C Janes, PhD

Research Sponsored by Mclean Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be aged 18-45.

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks after use

Awards & highlights

Study Summary

This trial aims to find out if using electronic cigarettes can help people become less sensitive to things that make them want to smoke.

Who is the study for?

This trial is for individuals aged 18-45 who smoke cigarettes daily, have a carbon monoxide level indicating regular smoking, and show some nicotine dependence. Participants must be willing to use Nicotine Replacement Therapy and e-cigarettes for 2-3 weeks, speak English, and pass an MRI safety screening.Check my eligibility

What is being tested?

The study aims to see if using both nicotine patches and electronic cigarettes can help reduce the urge to smoke when exposed to cues related to smoking. It involves monitoring reactions during an MRI scan.See study design

What are the potential side effects?

Potential side effects may include irritation from the nicotine patch or e-cigarette use such as throat/mouth discomfort or skin reactions at the patch site. The impact of dual usage on cravings or withdrawal symptoms will also be observed.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 45 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks after use

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks after use

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks after use for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Reduction in Cue Reactivity

Trial Design

1Treatment groups

Experimental Treatment

Group I: Dual nicotine patch and electronic cigaretteExperimental Treatment1 Intervention

Nicotine patch and the electronic cigarette will be administered.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Mclean HospitalLead Sponsor

213 Previous Clinical Trials

21,569 Total Patients Enrolled

Amy C Janes, PhDPrincipal InvestigatorMclean Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are researchers currently accepting participants for this study?

"As per clinicaltrials.gov, this specific trial is currently not accepting new participants. Although it was initially posted on January 1st, 2013 and last updated on October 29th, 2021. However, there are a total of 99 other ongoing clinical trials actively seeking eligible individuals to enroll at the moment."

Answered by AI

Is the age criterion for participation in this study limited to individuals above 70 years old?

"To be considered for this clinical trial, potential participants must fall within the age range of 18 to 45 years old. It's important to note that there are separate trials available specifically for patients under the age of 18 (5 trials) and those over the age of 65 (73 trials)."

Answered by AI

Recent research and studies

Experimental and Clinical PsychopharmacologyJournal

Brain Fmri Reactivity to Smoking-related Images Before and During Extended Smoking Abstinence.

Janes, Amy C., Blaise deB. Frederick, Sarah Richardt, Caitlin Burbridge, Emilio Merlo-Pich, Perry F. Renshaw, A. Eden Evins, Maurizio Fava, and Marc J. Kaufman. 2009. “Brain Fmri Reactivity to Smoking-related Images Before and During Extended Smoking Abstinence.”. Experimental and Clinical Psychopharmacology. American Psychological Association (APA). doi:10.1037/a0017797.

clinicaltrials.govStudy

Electronic Cigarettes and Reactivity to Smoking Cues

Scott Lukas 2013. "Electronic Cigarettes and Reactivity to Smoking Cues". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01782599.

All > Smoking > Paid Studies Massachusetts