Practice Quit Attempt for Nicotine Addiction

Phase-Based Progress Estimates
University of Pennsylvania, Philadelphia, PANicotine AddictionPractice Quit Attempt - Other
18 - 45
All Sexes
What conditions do you have?

Study Summary

This trial looks at how changes in brain activity and food intake may explain why people gain weight when they quit smoking.

Eligible Conditions
  • Nicotine Addiction

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Food intake is collected on days 1-4 and 29-32 of protocol

Day 4
Abstinence induced change in task BOLD signal change
Day 1
Abstinence induced change in Food Intake

Trial Safety

Trial Design

2 Treatment Groups

Non-Smoking Comparison Group
1 of 2
Smoker Group
1 of 2

Active Control

Experimental Treatment

56 Total Participants · 2 Treatment Groups

Primary Treatment: Practice Quit Attempt · No Placebo Group · N/A

Smoker Group
Experimental Group · 1 Intervention: Practice Quit Attempt · Intervention Types: Other
Non-Smoking Comparison GroupNoIntervention Group · 1 Intervention: Non-Smoking Comparison Group · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: food intake is collected on days 1-4 and 29-32 of protocol

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
1,869 Previous Clinical Trials
41,146,244 Total Patients Enrolled
8 Trials studying Nicotine Addiction
1,955 Patients Enrolled for Nicotine Addiction
James LougheadPrincipal Investigator - University of Pennsylvania
University of Pennsylvania

Eligibility Criteria

Age 18 - 45 · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are a smoker who wants to try to quit within the next 1-2 months and are motivated to do so. You need to rate your interest in quitting smoking as greater than 50 on a scale from 0 to 100.

Frequently Asked Questions

Is the eligibility for this research restricted to participants below 55 years of age?

"This research project is seeking participants between 18 and 45 years of age." - Anonymous Online Contributor

Unverified Answer

Am I an appropriate candidate for this medical research?

"To be considered for this trial, volunteers must demonstrate a dependence on tobacco and fall within the range of 18-45 years old. 100 participants are required to complete it satisfactorily." - Anonymous Online Contributor

Unverified Answer

Are researchers actively recruiting for participants in this investigation?

"According to the webpage for, this trial is open and actively recruiting participants. The original posting date was March 1st 2018 with a recent update posted on October 27th 2022." - Anonymous Online Contributor

Unverified Answer

How many people are enrolled in the clinical research?

"Affirmative. verifies that this clinical trial, which was initially made available on March 1st 2018, is indeed enrolling patients. This study requires the recruitment of 100 individuals from a single site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.