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Practice Quit Attempt for Nicotine Addiction (SIT Trial)

N/A

Waitlist Available

Led By James Loughead

Research Sponsored by University of Pennsylvania

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up food intake is collected on days 1-4 and 29-32 of protocol

Awards & highlights

SIT Trial Summary

This trial looks at how changes in brain activity and food intake may explain why people gain weight when they quit smoking.

Eligible Conditions

Nicotine Addiction

SIT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ food intake is collected on days 1-4 and 29-32 of protocol

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~food intake is collected on days 1-4 and 29-32 of protocol

This trial's timeline: 3 weeks for screening, Varies for treatment, and food intake is collected on days 1-4 and 29-32 of protocol for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Abstinence induced change in task BOLD signal change

Secondary outcome measures

Abstinence induced change in Food Intake

SIT Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Smoker GroupExperimental Treatment1 Intervention

The smokers group will be scanned on 2 occasions: (1) after a 4 day monitored practice quit attempt (biochemically verified), and (2) after 4 days of smoking as usual (order counterbalanced).

Group II: Non-Smoking Comparison GroupActive Control1 Intervention

Healthy non-smokers will complete one period (comparable to abstinence arm) of the study to serve as a baseline comparison group.

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Who is running the clinical trial?

University of PennsylvaniaLead Sponsor

2,000 Previous Clinical Trials

42,880,032 Total Patients Enrolled

8 Trials studying Nicotine Addiction

1,955 Patients Enrolled for Nicotine Addiction

James LougheadPrincipal Investigator - University of Pennsylvania

University of Pennsylvania

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the eligibility for this research restricted to participants below 55 years of age?

"This research project is seeking participants between 18 and 45 years of age."

Answered by AI

Am I an appropriate candidate for this medical research?

"To be considered for this trial, volunteers must demonstrate a dependence on tobacco and fall within the range of 18-45 years old. 100 participants are required to complete it satisfactorily."

Answered by AI

Are researchers actively recruiting for participants in this investigation?

"According to the webpage for clinicaltrials.gov, this trial is open and actively recruiting participants. The original posting date was March 1st 2018 with a recent update posted on October 27th 2022."

Answered by AI

How many people are enrolled in the clinical research?

"Affirmative. Clinicaltrials.gov verifies that this clinical trial, which was initially made available on March 1st 2018, is indeed enrolling patients. This study requires the recruitment of 100 individuals from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Neural Basis of Eating Behavior in Abstinent Smokers

James Loughead 2018. "Neural Basis of Eating Behavior in Abstinent Smokers". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03438188.