Mobile Health Intervention for Tobacco Cessation
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a mobile app called Living Free from Tobacco (LiFT) to help young adults quit nicotine and tobacco. The app has two versions: one builds psychological flexibility to support quitting, while the other provides educational content and resources about tobacco use and cessation. Participants will use the app and receive supportive text messages for three months. Individuals who have used nicotine or tobacco at least weekly in the past month and are interested in quitting might be a good fit for this study. As an unphased trial, this study presents a unique opportunity to explore innovative methods for quitting tobacco.
Do I have to stop taking my current medications to join the trial?
The trial does not specify whether you need to stop taking your current medications. However, you cannot be using other tobacco cessation treatments at the time of screening, but you can start them during the study.
What prior data suggests that the LiFT app is safe for young adults?
Research has shown that mobile apps like Living Free from Tobacco (LiFT) can help people quit smoking. Although specific safety data for the LiFT A and LiFT B apps is unavailable, studies on similar apps suggest they are generally safe. These apps assist users by managing cravings, tracking progress, and maintaining motivation. They typically don't cause harmful side effects, as they provide information and support through smartphones.
This trial is in the "Not Applicable" phase, indicating minimal risk since it doesn't involve new drugs or invasive treatments. Instead, it uses digital tools to promote positive behavior changes. Prospective participants can expect a safe experience aimed at helping them quit smoking with support from the app.12345Why are researchers excited about this trial?
Researchers are excited about the Mobile Health Intervention for Tobacco Cessation because it leverages innovative app-based technology to help people quit smoking. Unlike traditional methods like nicotine replacement therapy or counseling, the LiFT app uses interactive games, exercises, and educational content to engage users, especially young adults, with a personalized approach. The app also incorporates Acceptance and Commitment Therapy (ACT) techniques, which are tailored to help users manage cravings and mental health challenges. Additionally, participants receive supportive text messages, enhancing user engagement and providing continuous motivation, making this a comprehensive and accessible tool for tobacco cessation.
What evidence suggests that this trial's treatments could be effective for tobacco cessation?
Research has shown that smartphone apps can significantly aid in quitting smoking. Studies have found that using a smoking cessation app can double the chances of quitting, especially for those who use it consistently for several weeks. For instance, the SmartQuit 2.0 app helped 21% of its users quit smoking, outperforming attempts without assistance. In this trial, participants will use different versions of the LiFT app, which provide educational resources and tools tailored to young adults. While not every app works for everyone, those offering educational resources and enhancing mental flexibility can be effective. Using an app might increase the chances of quitting smoking, potentially reducing the risk of death from any cause by 11% to 34%.56789
Who Is on the Research Team?
Jaimee Heffner, PhD
Principal Investigator
Fred Hutch/University of Washington Cancer Consortium
Are You a Good Fit for This Trial?
This trial is for young adults aged 18-30 in the US who use nicotine or tobacco at least once a week, have internet access and a smartphone (Android 12+ or iPhone 11/iOS 17+), can read English, are not pregnant, not using other quit-tobacco treatments now, and are willing to use an app and complete study tasks.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
User-centered design and program development
Participants attend user testing interviews where they interact with LiFT app prototypes and provide feedback through think-aloud methods to support refinement of the intervention content and features.
Pilot trial
Participants use either the LiFT A or LiFT B app for 3 months, receiving associated text messages 2-3 times per week.
Post pilot trial diary study
Participants use the LiFT app and complete daily usability and satisfaction assessments for approximately 1 week, followed by a survey and interview.
Follow-up
Participants are monitored for satisfaction and effectiveness of the intervention after the pilot trial phase.
What Are the Treatments Tested in This Trial?
Interventions
- Living Free from Tobacco (LiFT) App
Trial Overview
The study compares two versions of a mobile app called LiFT to help young adults quit tobacco. One version focuses on psychological flexibility; the other provides educational content. Both include text messages and require participants to complete surveys and interviews.
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Active Control
Participants use the LiFT app and complete daily usability and satisfaction assessments for approximately 1 week. Participants also complete a survey and attend an interview.
Participants use the LiFT B app, which includes educational resources on preparing to quit, nicotine withdrawal, coping with withdrawal, mental health, along with health information videos, for 3 months. Participants also receive LiFT B text messages 2-3 times per week.
Participants use the LiFT A app, which includes interactive games and exercises, educational content, and tools tailored to young adults using an ACT treatment approach, for 3 months. Participants also receive LiFT A text messages 2-3 times per week.
Participants attend user testing interviews where they interact with LiFT app prototypes and provide feedback through think-aloud methods to support refinement of the intervention content and features.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Fred Hutchinson Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
Citations
Effectiveness of the Offer of the Smoke Free Smartphone App ...
Among motivated smokers provided with very brief advice to quit, the offer of the Smoke Free app did not have a detectable benefit for cessation compared with ...
The Effectiveness of Smartphone App–Based Interventions for ...
Quitting smoking reduces the risk of all-cause mortality by 11%-34%. Smartphone app–based smoking cessation (SASC) interventions have been developed and are ...
3.
news-medical.net
news-medical.net/news/20250814/Smartphone-app-doubles-quit-rates-among-low-income-smokers.aspxSmartphone app doubles quit rates among low-income ...
Not only were Smart-T users significantly more likely to quit smoking after six months compared to those using the QuitGuide app, we also found ...
The Effectiveness of Smartphone App–Based Interventions ...
Quitting smoking reduces the risk of all-cause mortality by 11%-34%. Smartphone app–based smoking cessation (SASC) interventions have been ...
5.
fredhutch.org
fredhutch.org/en/news/center-news/2016/11/smoking-cessation-app-smartquit-helps-break-habit-great-american-smokeout.htmlSmartQuit 2.0 app helps twice as many smokers cut habit
A smoking-cessation app developed through Fred Hutch research helped 21 percent of study users quit cigarettes — a success rate nearly three ...
LiFT - Apps on Google Play
Living Free from Tobacco (LiFT) is designed to motivate and support young adults to quit using tobacco. The Program is based on a new ...
A Novel Mobile Health Intervention for Improving Tobacco ...
This clinical trial compares two versions of a mobile health intervention called Living Free from Tobacco (LiFT), designed to support nicotine ...
Exploring relationships among smoking cessation app use, ...
Smoking cessation apps (SCAs) provide individuals with personalized quit plans, information about smoking cessation treatments, craving management strategies, ...
9.
tobaccopreventioncessation.com
tobaccopreventioncessation.com/Effectiveness-of-Mobile-Apps-for-Smoking-Cessation-Review,70088,0,2.htmlEffectiveness of Mobile Apps for Smoking Cessation
The review of eight selected studies illustrate the use of smartphone applications in increasing quit rates among smokers.
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