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Unpinning Termination therapy for Ventricular Tachycardia

N/A
Waitlist Available
Led By Daniel H. Cooper, MD
Research Sponsored by Cardialen, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during study procedure
Awards & highlights

Study Summary

This trial looks at the safety and effectiveness of a new heart rhythm treatment during ablation or ICD implant procedures.

Eligible Conditions
  • Ventricular Tachycardia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during study procedure
This trial's timeline: 3 weeks for screening, Varies for treatment, and during study procedure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Arrhythmia Termination as assessed by the number of episodes restored to sinus rhythm

Trial Design

1Treatment groups
Experimental Treatment
Group I: UPT TreatmentExperimental Treatment1 Intervention
Investigational therapy (UPT)

Find a Location

Who is running the clinical trial?

Cardialen, Inc.Lead Sponsor
5 Previous Clinical Trials
97 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,838 Previous Clinical Trials
47,851,648 Total Patients Enrolled
Washington University School of MedicineOTHER
1,937 Previous Clinical Trials
2,299,696 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Circulation: Arrhythmia and ElectrophysiologyJournal
Low-energy Multistage Atrial Defibrillation Therapy Terminates Atrial Fibrillation with Less Energy Than a Single Shock
Li, Wenwen, Ajit H. Janardhan, Vadim V. Fedorov, Qun Sha, Richard B. Schuessler, and Igor R. Efimov. 2011. “Low-energy Multistage Atrial Defibrillation Therapy Terminates Atrial Fibrillation with Less Energy Than a Single Shock”. Circulation: Arrhythmia and Electrophysiology. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/circep.111.965830.
Heart RhythmJournal
Termination of Sustained Atrial Flutter and Fibrillation Using Low-voltage Multiple-shock Therapy
Ambrosi, Christina M., Crystal M. Ripplinger, Igor R. Efimov, and Vadim V. Fedorov. 2011. “Termination of Sustained Atrial Flutter and Fibrillation Using Low-voltage Multiple-shock Therapy”. Heart Rhythm. Elsevier BV. doi:10.1016/j.hrthm.2010.10.018.
Journal of the American College of CardiologyJournal
Multistage Electrotherapy Delivered Through Chronically-implanted Leads Terminates Atrial Fibrillation with Lower Energy Than a Single Biphasic Shock
Janardhan, Ajit H., Sarah R. Gutbrod, Wenwen Li, Di Lang, Richard B. Schuessler, and Igor R. Efimov. 2014. “Multistage Electrotherapy Delivered Through Chronically-implanted Leads Terminates Atrial Fibrillation with Lower Energy Than a Single Biphasic Shock”. Journal of the American College of Cardiology. Elsevier BV. doi:10.1016/j.jacc.2013.07.098.
American Journal of Physiology-Heart and Circulatory PhysiologyJournal
Mechanisms of Unpinning and Termination of Ventricular Tachycardia
Ripplinger, Crystal M., Valentin I. Krinsky, Vladimir P. Nikolski, and Igor R. Efimov. 2006. “Mechanisms of Unpinning and Termination of Ventricular Tachycardia”. American Journal of Physiology-heart and Circulatory Physiology. American Physiological Society. doi:10.1152/ajpheart.01300.2005.
~1 spots leftby Apr 2025
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