Mineral Sunscreens for Skin Tone Lightening
Trial Summary
Do I need to stop taking my current medications to join the trial?
The trial protocol does not specify if you must stop taking your current medications. However, if you are taking a medication that could mask an adverse event or confuse the study results, you may be excluded from participating.
What data supports the idea that Mineral Sunscreens for Skin Tone Lightening is an effective treatment?
The available research shows that mineral sunscreens containing titanium dioxide and zinc oxide are effective in providing broad-spectrum protection against UV radiation. These ingredients are used in sunscreens to block harmful UV rays, which can help prevent skin damage and maintain an even skin tone. The research highlights that nano-sized versions of these minerals offer superior UV protection and reduce the whitening effect on the skin, making them more cosmetically appealing. Additionally, while these sunscreens are effective against UV radiation, they do not protect against visible light, which can also affect skin tone. Tinted sunscreens, which include iron oxides, are recommended for protection against visible light and are beneficial for conditions like hyperpigmentation. Overall, mineral sunscreens are effective for UV protection, but for comprehensive skin tone lightening, additional ingredients may be needed to address visible light exposure.12345
What safety data exists for mineral sunscreens used for skin tone lightening?
The safety data for mineral sunscreens, specifically those containing nano-sized titanium dioxide (TiO2) and zinc oxide (ZnO), indicate that these ingredients are generally considered safe for use in sunscreens. Studies show that these nanoparticles do not penetrate beyond the outer layer of the skin (stratum corneum) and are unlikely to cause harm. The risk to humans from using these nano-structured UV filters is considered negligible, and they are safe for use at concentrations up to 25% in cosmetic products. Despite some public concerns about 'nano' technology, the benefits of using these sunscreens outweigh potential safety concerns.12567
Is Sunscreen A, B, or C a promising treatment for skin tone lightening?
Yes, Sunscreen A, B, or C, which contain zinc oxide and titanium dioxide, are promising treatments. They provide strong protection against harmful UV rays, which can help prevent skin damage and support skin tone lightening. These sunscreens use nanoparticles to offer better UV protection and reduce the white appearance on the skin, making them more effective and cosmetically appealing.12345
What is the purpose of this trial?
The purpose of the study is to evaluate the whitening potential of different mineral and chemical sunscreens across multi-cultural skin tones through instrumentation, imaging, and self-assessment. It also aimed to evaluate the relationship between self-perception and objective measurements of whitening.
Eligibility Criteria
This trial is for individuals of various cultural backgrounds interested in testing the whitening effects of different sunscreens. Participants should be willing to use these sunscreens and provide feedback on their experience.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants apply assigned sunscreen to lower legs, face, and volar forearms, with measurements taken at specified intervals
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Sunscreen A
- Sunscreen B
- Sunscreen C
Sunscreen A is already approved in United States, European Union for the following indications:
- Prevention of sunburn
- Protection against UV radiation
- Prevention of sunburn
- Protection against UV radiation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johnson & Johnson Consumer Inc. (J&JCI)
Lead Sponsor