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Solar Simulated Light (SSL) for Sun Damage

N/A
Waitlist Available
Led By Clara Curiel, MD
Research Sponsored by University of Arizona
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (pre-ssl exposure) and post-ssl exposure (at 5hr and 24hr post-exposure).
Awards & highlights

Study Summary

This trial will help researchers learn more about how solar light affects human skin and could lead to new ways to prevent skin cancer.

Eligible Conditions
  • Sun Damage

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (pre-ssl exposure) and post-ssl exposure (at 5hr and 24hr post-exposure).
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (pre-ssl exposure) and post-ssl exposure (at 5hr and 24hr post-exposure). for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Malignant Neoplasms
To assess changes in skin cancer signaling pathway activation levels pre-solar simulated light exposure (baseline) and 5hr and 24hr post-solar simulated light exposure in sun damaged skin.
Secondary outcome measures
Exploratory Endpoint: To assess the correlation between skin sun damage level and the magnitude of solar simulated light-induced pathway activation.

Trial Design

1Treatment groups
Experimental Treatment
Group I: TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated LightExperimental Treatment1 Intervention
We have one arm, which consists of participants with a broad range of sun damage on the forearm. Based on the standardized clinical photodamage scale (Hu C, Curiel-Lewandrowski C. Archives of Dermatology, 2011; 147(1):31-36), we will include mild (N=12), moderate (N=12), and severely (N=12) sun damaged skin.

Find a Location

Who is running the clinical trial?

University of ArizonaLead Sponsor
514 Previous Clinical Trials
148,240 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,122 Total Patients Enrolled
Clara Curiel, MDPrincipal InvestigatorUniversity of Arizona
2 Previous Clinical Trials
33 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light
2020. "An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05398237.
~6 spots leftby Apr 2025
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