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Cognitive Processing Therapy + Crisis Response Plan for PTSD with Suicidal Thoughts
N/A
Waitlist Available
Led By Craig Bryan, PsyD
Research Sponsored by Ohio State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (pretreatment), 1 week, 2 weeks, 26 weeks, 52 weeks
Awards & highlights
Study Summary
This trial will test whether adding a crisis response plan to cognitive processing therapy can help reduce suicide ideation among suicidal veterans and prevent the development of suicide ideation among veterans who don't have it when they start the therapy.
Who is the study for?
This trial is for U.S. military veterans aged 18 or older who can speak and understand English and are able to consent to the study. Participants must have PTSD or subthreshold PTSD but cannot be at immediate risk of suicide requiring hospitalization, nor can they have a substance use disorder needing medical management.Check my eligibility
What is being tested?
The study tests if adding a Crisis Response Plan (CRP) to Cognitive Processing Therapy (CPT) helps reduce suicidal thoughts more quickly in veterans with PTSD. It also checks if this combination prevents new cases of suicidal thoughts during or after treatment.See study design
What are the potential side effects?
While not explicitly listed, potential side effects may include emotional distress due to discussing traumatic events during therapy sessions, which could temporarily increase symptoms like anxiety or depression.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline (pretreatment), 1 week, 2 weeks, 26 weeks, 52 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (pretreatment), 1 week, 2 weeks, 26 weeks, 52 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in suicide ideation
Percent with follow-up suicidal behaviors
Secondary outcome measures
Change in PTSD symptoms
Change in psychiatric symptoms
Change in psychological well-being
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Crisis Response Plan (CPT+CRP)Experimental Treatment3 Interventions
Participants will receive cognitive processing therapy (CPT) for PTSD combined with a collaborative crisis response plan (CRP). The CRP includes many of the same elements as the safety plan (i.e., warning signs, self-management strategies, sources of social support, crisis services), but is created collaboratively by the patient with active input of their clinician rather than being self-guided. The CRP also includes a section focused on the participant's reasons for living, an addition that has been shown to increase positive emotional states (e.g., hope, optimism) and lead to faster reductions in suicidal intent. The CRP will be collaboratively created during the first therapy session.
Group II: Treatment As UsualActive Control2 Interventions
Participants will receive cognitive processing therapy (CPT) for PTSD combined with a self-guided safety plan. As a recommended standard care practice with suicidal patients, the combination of CPT and safety plan represents treatment as usual. The safety plan will be assigned during the first therapy session.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Processing Therapy (CPT)
2019
Completed Phase 3
~1400
Find a Location
Who is running the clinical trial?
Ohio State UniversityLead Sponsor
828 Previous Clinical Trials
505,601 Total Patients Enrolled
Craig Bryan, PsyDPrincipal InvestigatorOhio State University
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You have a drug addiction that requires medical treatment.You have a high risk of harming yourself and require immediate hospitalization or specialized treatment for suicidal thoughts.You have been diagnosed with PTSD or are experiencing symptoms that are close to meeting the criteria for PTSD.
Research Study Groups:
This trial has the following groups:- Group 1: Treatment As Usual
- Group 2: Crisis Response Plan (CPT+CRP)
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there still vacancies for individuals to participate in this experiment?
"As indicated on clinicaltrials.gov, this trial has ceased patient recruitment. The study was first published in January 2021 and last updated in April 2022; however, there are over 200 other trials currently searching for participants."
Answered by AI
Who else is applying?
What state do they live in?
Ohio
How old are they?
18 - 65
What site did they apply to?
The Ohio State University
What portion of applicants met pre-screening criteria?
Met criteria
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