Treatment for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Oregon Health and Science University, Portland, OR
Depression+1 More
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether an online screening and anonymous interaction with a clinician may help reduce stress, depression, substance use, and suicidal thoughts in distressed medical residents, fellows, and faculty.

See full description

Eligible Conditions

  • Depression
  • Suicide

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 5 primary outcomes in patients with Depression. Measurement will happen over the course of at enrollment for treatment (intake appointment).

Time survey is completed by trainee or faculty member at baseline
ISP levels of distress seen with medical trainees and faculty
at enrollment for treatment (intake appointment)
Demographics of residents and faculty physicians who seek counseling through in house program
Month 6
Who responds to treatment-clinician rating of suicide risk
Month 6
Who responds to treatment--level of distress
Month 6
Who responds to treatment-level of burnout

Trial Safety

Safety Progress

1 of 3

Trial Design

0 Treatment Group

This trial requires 4000 total participants across 0 different treatment group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: time of intake to participants' end of treatment or 6 months since last seen
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly time of intake to participants' end of treatment or 6 months since last seen for reporting.

Who is running the study

Principal Investigator
S. E. P.
Prof. Sydney Ey Ph.D., Professor, Psychiatry, Resident and Faculty Wellness
Oregon Health and Science University

Closest Location

Oregon Health and Science University - Portland, OR

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
OHSU medical residents, fellows, and full-time School of Medicine faculty

Patient Q&A Section

What causes depression?

"This may be partially due in part to adverse events associated with a variety of psychiatric medications. The combination of the use of many antidepressants and other medication may also negatively impact mental health. However, it is unclear whether the use of antidepressants alone or alone with other drug therapy is responsible for the development of depression." - Anonymous Online Contributor

Unverified Answer

What are common treatments for depression?

"There are several effective treatments for depression. The primary treatment of choice should be tailored to the age and presentation of a specific patient. Selective serotonin reuptake inhibitor (SSRI), selective norepinephrine reuptake inhibitor (SNRI), tricyclic antidepressive agents, MAO inhibitors, and electroconvulsive therapy (ECT) are all used to treat mild or moderate depression. The use of ECT and/or medications is recommended only as alternative alternatives to pharmacotherapy. Medication monotherapy is the most popular option, although there are certain types that can be used as standalone or complementary therapy options. If non-pharmacological treatment is needed, patient compliance is an issue." - Anonymous Online Contributor

Unverified Answer

What is depression?

"Depression is a serious disturbance of mood that is characterised primarily by a sense of sadness, pessimism and anxiety and often leads to decreased energy levels, poor health and social isolation. It is also associated with poor sleep and an increased risk of suicide. Approximately 10% of Europeans and Americans are currently diagnosed with depression." - Anonymous Online Contributor

Unverified Answer

How many people get depression a year in the United States?

"The current study estimated that there existed nearly 18 million people in the United States who had depression at some point in their life, making it the most common mental disorder in Americans." - Anonymous Online Contributor

Unverified Answer

What are the signs of depression?

"If a person is being evaluated in a healthcare setting for anything other than routine medical procedures, it is very important to make a good evaluation and a diagnosis. Signs of depression include low self rating of one's own quality of life, changes in appetite, sleep patterns, and even irritability should be evaluated and should be considered when there is an unexplained pattern of changes in the person’s mood. When a patient is not responding to the usual treatment such as an antidepressant, then evaluation should be considered in order to understand another cause of the issues that the person is experiencing. It is important to remember that the signs and symptoms of depression include changes in sleep patterns, loss of appetite, fatigue, and even thoughts about suicide." - Anonymous Online Contributor

Unverified Answer

Can depression be cured?

"The study supports the fact that the way how the disease is diagnosed can decide the chances of having a favorable prognosis. It has been found that at an early time when it is diagnosed, and even if only diagnosed and treated, this disease can be controlled, and with proper treatment in a long period it can be cured. However, that doesn't apply to the psychiatric patients who are treated later. They get worse over time, if not treated properly, without taking proper medication. There is a need for taking appropriate treatments for the depression patients and they can be cured when they get treated early and get the treatment in time in order to cure." - Anonymous Online Contributor

Unverified Answer

How serious can depression be?

"Symptoms of major depression vary widely and can be both acute and chronic in nature. The duration of illness should be considered when diagnosing and treating symptoms of depression." - Anonymous Online Contributor

Unverified Answer

Does treatment improve quality of life for those with depression?

"Quality of life improves in those receiving treatment for severe depression. The impact of depression on quality of life is not fully explored. Findings suggest other domains than QOL could be improved, such as patient perceptions of stigma and perceptions of the illness. Longer studies of the effects on QOL and the factors that affect those effects are needed." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for depression?

"Clinicians' opinions and attitudes could be improved with a training program. This would result in increased interest in clinical trials for depression and help clinicians to be more confident about the feasibility of the trial, and more open-minded to the ethical aspects of the trial." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in treatment for therapeutic use?

"The most notable and rapidly progressing field for newer and deeper insight into mood disorders treatment is the field of epigenomics. It is a field that, among many other important new insights, leads to the hope that new medicines will be developed that target specific targets of our epigenetic marks, rather than aiming to treat the underlying disease of a certain disease type only." - Anonymous Online Contributor

Unverified Answer

What is the latest research for depression?

"The number of therapies studied has increased since 1980 - it is time for new research to be conducted - at the same time we need to be careful in interpreting what the available data shows and how it helps to explain the discrepancy between reported rates of depression and epidemiological data. There is also a need to reflect on the validity - the generalisability - of our findings and of the relevance of our current methods to explaining the epidemiological findings of our field." - Anonymous Online Contributor

Unverified Answer

What is treatment?

"Treatment is more than just medication. The patient and doctors decide on treatment together. Depression, or no treatment, is not an option. I hope this paper is useful to a depressed patient who happens to be in remission or who just can't find a way to deal with depressed thoughts. I'm sure I would understand." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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