Benzodiazepine Use During Cardiac Surgery for Postoperative Delirium
(B-Free Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing if using less of a sedative drug during heart surgery can reduce confusion afterward. It focuses on adults having open heart surgery, as many experience confusion post-surgery. The study aims to see if reducing this drug can prevent such confusion.
Who Is on the Research Team?
Jessica Spence, MD FRCPC
Principal Investigator
Population Health Research Institute
Eric Jacobsohn, MBChB MPHE
Principal Investigator
University of Manitoba
Stuart Connolly, MD FRCPC
Principal Investigator
Population Health Research Institute
Are You a Good Fit for This Trial?
This trial is for adults over 18 years old who are undergoing cardiac surgery at hospitals performing at least 250 such surgeries a year. These hospitals must also routinely check patients for postoperative delirium using standard methods and agree to follow the study's benzodiazepine use policy.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo cardiac surgery with either a liberal or limited benzodiazepine policy
Follow-up
Participants are monitored for incidence of delirium and other outcomes post-surgery
Extended Follow-up
Participants' length of stay in ICU and hospital is monitored, along with in-hospital mortality
What Are the Treatments Tested in This Trial?
Interventions
- Benzodiazepine-free Cardiac Anesthesia
Find a Clinic Near You
Who Is Running the Clinical Trial?
Population Health Research Institute
Lead Sponsor