Acupressure for Iatrogenic Withdrawal Syndrome

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Vanderbilt University Medical Center, Nashville, TN
Iatrogenic Withdrawal Syndrome+1 More
Acupressure - Other
Eligibility
Any Age
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether auricular acupressure might help prevent Iatrogenic Withdrawal Syndrome in infants.

See full description

Eligible Conditions

  • Iatrogenic Withdrawal Syndrome

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Iatrogenic Withdrawal Syndrome

Study Objectives

This trial is evaluating whether Acupressure will improve 1 primary outcome in patients with Iatrogenic Withdrawal Syndrome. Measurement will happen over the course of 24 months.

24 months
Intervention pilot feasibility study will assess the impact of auricular acupressure

Trial Safety

Safety Progress

1 of 3

Other trials for Iatrogenic Withdrawal Syndrome

Trial Design

2 Treatment Groups

No Intervention
1 of 2
Intervention
1 of 2
Active Control
Experimental Treatment

This trial requires 40 total participants across 2 different treatment groups

This trial involves 2 different treatments. Acupressure is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Intervention
Other
Acupressure stickers will be applied to one ear in accordance with the NADA protocol acupuncture technique.
No InterventionNo intervention

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 24 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 24 months for reporting.

Who is running the study

Principal Investigator
H. J.
Heather Jackson, Advanced Practiced Leader & Nurse Practitioner
Vanderbilt University Medical Center

Closest Location

Vanderbilt University Medical Center - Nashville, TN

Eligibility Criteria

This trial is for patients born any sex of any age. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Exposure to opioids and/or benzodiazepine medications for 5 days or more
Maternal age of 18 or older
Infants, 34 weeks or greater gestation
Beginning a stable wean

Patient Q&A Section

How many people get withdrawal symptoms a year in the United States?

"Approximately one in three medical patients meet the criteria for withdrawal symptoms at some time. The incidence of acute withdrawal symptoms is highest in those at high risk for withdrawal symptoms from medication or addiction." - Anonymous Online Contributor

Unverified Answer

What are common treatments for withdrawal symptoms?

"Various types of treatment have been used for withdrawal symptom, and no one has been proven 100 per cent effective. Medications are often effective. For most of the more serious or prolonged post-acute phase syndromes, behavioural treatment is the only satisfactory solution while awaiting more refined pharmacological treatments." - Anonymous Online Contributor

Unverified Answer

What is withdrawal symptoms?

"Withdrawal includes many different symptoms (physical, emotional, perceptual, behavioural, and cognitive) that result from cessation of a medication. Patients with a diagnosis should be advised on strategies to maximize the effectiveness of stopping medication prior to cessation. Patients not experiencing withdrawal symptoms should restart treatment or continue treatment as needed, when necessary." - Anonymous Online Contributor

Unverified Answer

What causes withdrawal symptoms?

"Withdrawal symptoms may be due to any one of a combination of factors, and thus are not necessarily due to any one medical condition. Withdrawal symptoms can be a normal reaction to drug use or a symptom that warrants further evaluation and treatment.\n" - Anonymous Online Contributor

Unverified Answer

Can withdrawal symptoms be cured?

"Although many people in our sample experienced significant short-term withdrawal effects, after adjusting for age and baseline symptoms, they reported significant improvements in functioning that were maintained or increased when compared with naturalistic controls." - Anonymous Online Contributor

Unverified Answer

What are the signs of withdrawal symptoms?

"As a group no signs of withdrawal have been reported. However, most withdrawal symptoms are likely to be evident within the first few days of cessation of drug use if it is in its period of action. However, when withdrawal does occur it may be mild, moderate or severe. The severity of withdrawal symptoms can also vary from person to person. Patients with a history of a physical disease are particularly likely to experience withdrawal and are usually more severely affected. Patients with a history of drug taking disorders often experience less severe withdrawal symptoms.\nsubjective assessments can be used to monitor treatment." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of acupressure?

"Acupressure is a low risk therapy that is generally well tolerated when used as a form of acupuncture. However, there are a number of possible side effects for acupressure; these are all associated with the underlying principle of pressure exerted on the body. In a study of 1572 patients attending for initial assessment at a GP surgery, this showed that of the 545 adverse events of acupressure reported by patients, only 6 were serious adverse events and 37 were milder adverse events. Adverse effects were more common for men, for the elderly, for patients with cardiovascular conditions and for the Asians." - Anonymous Online Contributor

Unverified Answer

What is acupressure?

"Acupressure therapy may reduce pain and improve health-related quality of life. But the [quality of evidence is low, and most studies have small sample sizes and limited blinding, with varying treatment doses, and varying times and frequencies of treatments. Also, the conclusions were based mostly on uncontrolled studies with unrepresentative population, uncontrolled time points, and inadequate reporting." - Anonymous Online Contributor

Unverified Answer

How does acupressure work?

"Results from a recent clinical trial of this study show that acupressure treatment results in significant reduction in [withdrawal symptoms due to pain in patients with cancer and other chronic illnesses, including heart failure, COPD, asthma, and arthritis, and it is efficacious when given on an outpatient basis in addition to the patient's existing medical therapy] and is considered to be useful for chronic pain in [chronic illnesses]." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving acupressure?

"Acupressure is a relatively new and inexpensive procedure. The treatment is available in most health care facilities as most clinicians are trained in acupuncture and may be comfortable prescribing this treatment to their patients. To date, there is a limited amount of relevant published and peer-reviewed research on acupressure, and thus future research to evaluate and compare acupressure would be warranted." - Anonymous Online Contributor

Unverified Answer

What does acupressure usually treat?

"A significant proportion of our patients reported little or no improvement from acupressure. These patients often reported using acupressure to avoid adverse effects and drug interactions with other medications. Using acupressure to treat symptoms of diabetes and chronic conditions may not be effective, and requires further investigation." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of withdrawal symptoms?

"It is important to examine the context of withdrawal before considering any possible cause. In the case of abrupt cessation of dopamine agonist therapy with [naloxone] withdrawal symptoms are highly unlikely to be caused by the opioid agonist used. In the case of abrupt discontinuation of therapy with [naloxone] or other short-acting dopamine agonists withdrawal symptoms are highly unlikely to be caused by the opioid antagonist or the opioid used. Patients using [naloxone] or longer-acting dopamine agonists can experience withdrawal when switching to another treatment. Withdrawal due to cessation of dopamine agonist therapy usually occurs over a period of weeks to months." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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