Genetic Factors for Substance Use Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how genes influence addictive behaviors and substance abuse, focusing on attention, memory, and emotional responses. Researchers will collect genetic information through a blood sample to examine its impact on brain imaging results and behaviors linked to addiction. This trial suits adults currently participating in other National Institute on Drug Abuse studies, whether they are healthy nonsmokers, smokers, or dealing with substance use or psychiatric disorders. Participants will provide a blood sample, answer questions about mood and memory, and possibly engage in tasks like computer games.
As an unphased study, this trial offers a unique opportunity to contribute to groundbreaking research on addiction and genetics.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does exclude people using certain medications that might interfere with MRI results. It's best to discuss your specific medications with the study team.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover how variations in our genes can affect medical imaging results. Unlike typical treatments that focus on changing the course of a disease, this trial looks at collecting genetic information to better understand how different people’s bodies react to imaging techniques. By identifying specific genetic factors, researchers hope to personalize imaging and improve the accuracy and effectiveness of diagnosis and monitoring for various conditions. This could lead to more tailored treatment plans and better outcomes for patients in the future.
Who Is on the Research Team?
Betty Jo Salmeron, M.D.
Principal Investigator
National Institute on Drug Abuse (NIDA)
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Main Study
Participants provide a blood sample, complete questionnaires, and perform behavioral tasks. MRI scans may be conducted.
CTN Pilot Study
Participants complete a phenotyping battery developed by the NIDA CTN, overlapping with main protocol assessments.
Follow-up
Participants are monitored for safety and effectiveness after the main study procedures.
What Are the Treatments Tested in This Trial?
Interventions
- Collection of Genetic Information
Find a Clinic Near You
Who Is Running the Clinical Trial?
National Institute on Drug Abuse (NIDA)
Lead Sponsor