Your session is about to expire
← Back to Search
Non-invasive Brain Stimulation
Brain and Hand Stimulation for Stroke Recovery
N/A
Recruiting
Research Sponsored by Amit Sethi
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age between 18-80 years
Male or female (either right or left handed) with unilateral hemiparesis after stroke
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 6 weeks
Awards & highlights
Study Summary
This trial will study how repeatedly pairs brain and hand stimulation affects the brain's plasticity and a person's ability to perform daily tasks after suffering a stroke.
Who is the study for?
This trial is for adults aged 18-80 who've had a stroke at least six months ago, resulting in moderate-to-severe hand weakness but can still grasp. They must be able to follow instructions and have no severe spasticity, seizures, concurrent therapies that could affect results, or metal implants that interfere with MRI scans.Check my eligibility
What is being tested?
The study tests how brain and hand stimulation together might help improve hand movement after a stroke. It looks at changes in the brain's plasticity and motor performance by synchronizing non-invasive brain stimulation with electrical stimulation of the hand.See study design
What are the potential side effects?
Potential side effects may include discomfort from the electrical stimulation on the hand, headache or scalp discomfort from brain stimulation, tingling sensations due to nerve excitation, and risks typically associated with MRI procedures.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 80 years old.
Select...
I have weakness on one side of my body due to a stroke.
Select...
I can grasp objects with my hand.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline to 6 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 6 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Box and block test
Secondary outcome measures
Hand force
Motor evoked potential
Trial Design
1Treatment groups
Experimental Treatment
Group I: Combined non-invasive brain and Functional Electrical StimulationExperimental Treatment1 Intervention
In this arm of the study participants will receive repeated non-invasive brain stimulation synchronously paired with FES
Find a Location
Who is running the clinical trial?
Amit SethiLead Sponsor
2 Previous Clinical Trials
54 Total Patients Enrolled
2 Trials studying Stroke
54 Patients Enrolled for Stroke
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have trouble feeling touch and knowing where your body parts are, which may make it hard for you to tell if you are experiencing too much tingling from hand stimulation.You have metal implants in your head or neck that could interfere with the treatment.You have trouble with memory or thinking that might make it hard to follow the study instructions.I am between 18 and 80 years old.I have weakness on one side of my body due to a stroke.I struggle to stay still or alert during an MRI.You weigh more than 300 pounds because the MRI machine cannot accommodate larger body sizes.You are not expected to live for the entire duration of the study.I have severe stiffness in my wrist and fingers that makes it hard to open my hand.I am an adult seeking treatment for stroke.I have a psychiatric condition or take medication that could affect the study.I experience severe pain in my arm, rated 5 or more, which could hinder my study participation.You have trouble speaking and understanding simple instructions.I have never had seizures or epilepsy.I had a stroke more than six months ago.You are receiving other treatments that could affect the study results.I have a condition like arthritis in my hand that limits movement.I have trouble noticing my affected hand.I can grasp objects with my hand.The ability to produce a response in the Extensor digitorum communis (EDC) muscle when stimulated.I have a neurological condition that is not a stroke.You have a history of specific mental health conditions like schizophrenia or bipolar disorder, or you are currently experiencing moderate to severe depression.
Research Study Groups:
This trial has the following groups:- Group 1: Combined non-invasive brain and Functional Electrical Stimulation
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What are the qualifications to participate in this research experiment?
"To enroll in this clinical trial, prospective patients must have had a stroke and be between 18-80 years of age. A total of 20 participants are currently needed to join the study."
Answered by AI
What is the scope of this analysis with regards to participants?
"Affirmative. According to clinicaltrials.gov, this research project has resumed enrolment since October 1st 2020 and was most recently modified on August 1st 2022. The study aims to recruit a total of 20 volunteers at one single medical facility."
Answered by AI
Is the age limit for enrolment in this trial restricted to individuals over twenty?
"According to the eligibility requirements, potential participants must be at least 18 years old and no older than 80."
Answered by AI
Are there still vacancies available for prospective participants of this clinical trial?
"Clinicaltrials.gov data suggests that this research investigation is currently enrolling participants. The trial was first announced on October 1st 2020, and its information was most recently updated on August 1st 2022."
Answered by AI
Who else is applying?
What state do they live in?
Pennsylvania
What site did they apply to?
Neuromotor Recovery and Rehabilitation Lab
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger