126 Participants NeededMy employer runs this trial

Multimodal Exercise Training for Stroke

(PROTECT Trial)

Recruiting at 1 trial location
MR
Overseen ByMarc Roig
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: McGill University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The rates of cognitive decline and dementia after stroke are disproportionately high. Strategies that can protect the brain early after the stroke event could reduce the future risk of cognitive decline and dementia in these patients. Although physical exercise is usually recommended after stroke, there is very little information about the protective effect of exercise implemented in early stages of recovery as a potential protective measure against cognitive decline and dementia risk in these patients. This study will investigate the effect of a multimodal exercise intervention implemented early after the stroke event on cognition and on a selected group of markers that can predict cognitive decline and dementia risk.

Who Is on the Research Team?

MR

Marc Roig

Principal Investigator

McGill University

Are You a Good Fit for This Trial?

Inclusion Criteria

I had my first stroke within the last 6 months, confirmed by MRI or CT scan.
I can walk at least 10 meters on my own and follow instructions.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo 12 weeks of multimodal exercise training or balance, toning, and stretching training

12 weeks
3 visits per week (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months
Assessments at 6 and 12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Multimodal Training

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Multimodal ExerciseExperimental Treatment1 Intervention
Group II: Balance, Toning and StretchingActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

McGill University

Lead Sponsor

Trials
421
Recruited
1,017,000+

Jewish Rehabilitation Hospital

Collaborator

Trials
7
Recruited
810+

Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal

Collaborator

Trials
17
Recruited
3,400+

Montreal Neurological Institute and Hospital

Collaborator

Trials
7
Recruited
2,200+

McMaster University

Collaborator

Trials
936
Recruited
2,630,000+