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Less-Impaired Arm Training for Stroke

N/A

Waitlist Available

Led By Robert L Sainburg, Phd, OTR

Research Sponsored by Robert L. Sainburg

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Demonstrates cognitive abilities

Neuroradiological confirmation of unilateral brain damage with residual contralesional upper-extremity weakness

Timeline

Screening 3 weeks

Treatment Varies

Follow Up within 1 week following last treatment session

Awards & highlights

Study Summary

This trial will test if improving the speed, coordination, and accuracy of the less-impaired arm can improve functional independence for people with chronic stroke.

Who is the study for?

This trial is for chronic stroke survivors with confirmed unilateral brain damage and weakness in the opposite arm. They must be at least 6 months post-stroke, able to perform tasks with their less-impaired arm, and have no major psychiatric disorders, other neurological diseases, bilateral strokes, or substance abuse history.Check my eligibility

What is being tested?

The study tests if intensive training focused on improving speed, coordination, and accuracy of the less-impaired arm can enhance functional independence in individuals who have had a stroke.See study design

What are the potential side effects?

Since this trial involves physical training exercises rather than medication or invasive procedures, side effects may include muscle soreness or fatigue related to increased activity levels during rehabilitation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My thinking and memory skills are functioning well.

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I have brain damage on one side and weakness in the opposite arm.

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It has been over 6 months since my stroke.

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I have difficulty using my arm on the same side as my injury.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ within 1 week following last treatment session

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~within 1 week following last treatment session

This trial's timeline: 3 weeks for screening, Varies for treatment, and within 1 week following last treatment session for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change from baseline on ABILHAND

Change from baseline on Barthel Index

Change from baseline on Jebsen-Taylor Hand Function Test Test

+1 more

Secondary outcome measures

Change from baseline on FIM-motor subscale

Change from baseline on Position Variability

Change from baseline on Work Space Area

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Less-Impaired Arm TrainingExperimental Treatment1 Intervention

Intervention condition includes therapy of the less-impaired (ipsilesional) arm.

Group II: Contralesional Arm ComparisonPlacebo Group1 Intervention

Comparison control condition includes therapy of the paretic (contralesional) arm.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Less-Impaired Arm Training

2019

N/A

~60

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Southern CaliforniaOTHER

905 Previous Clinical Trials

1,596,265 Total Patients Enrolled

22 Trials studying Stroke

5,015 Patients Enrolled for Stroke

Penn State UniversityOTHER

355 Previous Clinical Trials

125,704 Total Patients Enrolled

Robert L. SainburgLead Sponsor

Media Library

Less-Impaired Arm Training Clinical Trial Eligibility Overview. Trial Name: NCT03634397 — N/A

Stroke Research Study Groups: Less-Impaired Arm Training, Contralesional Arm Comparison

Stroke Clinical Trial 2023: Less-Impaired Arm Training Highlights & Side Effects. Trial Name: NCT03634397 — N/A

Less-Impaired Arm Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT03634397 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are being enrolled in this medical trial?

"Affirmative. According to clinicaltrials.gov, this research project which was initially shared on February 2nd 2019 is actively searching for test subjects. A total of 120 individuals must be gathered from two distinct medical centres in order to continue the trial."

Answered by AI

Is enrollment open for this trial at present?

"According to clinicaltrials.gov, this scientific study is currently inviting participants. The investigation was initially published on February 2nd 2019 and most recently revised on September 28th 2022."

Answered by AI

What criteria must be met to qualify for participation in this clinical trial?

"This medical trial is enrolling 120 individuals, aged 18-85 with confirmed unilateral brain damage caused by a stroke. To be eligible for the study, participants must also possess preserved cognitive faculties and demonstrate contralesional upper limb weakness as assessed by JTHFT in addition to being 6+ months post-stroke."

Answered by AI

What are the key aims of this clinical experiment?

"This trial's primary purpose is to assess the impact of treatment on Upper-Extremity Fugl-Meyer Assessment through two pre-treatment tests (1 week apart) and three post tests: 1 following last session, 2 weeks after intervention completion, and 6 months later. Secondary objectives include evaluating FIM motor subscale for self care activities burden; position variability early/late in movement; kinematic variability during reaching movements."

Answered by AI