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Mental Toughness Training for Stress (TUtough Trial)

N/A
Waitlist Available
Led By Robin Aupperle, PhD
Research Sponsored by Laureate Institute for Brain Research, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up average across all time points from post-training (average of 4 weeks after baseline) to the last semester they are enrolled at the university, (on average 3.5 years after baseline).
Awards & highlights

TUtough Trial Summary

This trial assesses how mental toughness training helps first-year university students' mental health, behavior and academic success, plus how genetics affect response to the training.

TUtough Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and completion of training, on average after 4 weeks.
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and completion of training, on average after 4 weeks. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Connor---Davidson Resilience Scale (CD---RISC 10)
Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety Scale
Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Scale
+2 more
Secondary outcome measures
Change in percent signal change within anatomically-defined medial prefrontal cortex, amygdala, dorsolateral prefrontal cortex, anterior insula, and ventral striatum.
National Institute of Health Toolbox Perceived Stress Scale
Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety Scale
+2 more

TUtough Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Mental Toughness TrainingExperimental Treatment1 Intervention
Behavioral training in goal-building, mindfulness, and the growth mindset.
Group II: College as UsualActive Control1 Intervention
no training provided
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Mental Toughness Training
2016
N/A
~540

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Who is running the clinical trial?

Laureate Institute for Brain Research, Inc.Lead Sponsor
50 Previous Clinical Trials
4,807 Total Patients Enrolled
Robin Aupperle, PhDPrincipal InvestigatorLaureate Institute for Brain Research
4 Previous Clinical Trials
198 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~63 spots leftby Apr 2025