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Cottonseed Oil for Metabolic Syndrome, Inflammation, and Oxidative Stress

N/A
Waitlist Available
Led By Mary P. Miles, PhD
Research Sponsored by Montana State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 month
Awards & highlights

Study Summary

This trial will test the effects of consuming cottonseed oil (CSO) on oxidative stress, inflammation, and bile acids in humans. The hypothesis is that CSO will have greater benefits than olive oil for these conditions.

Eligible Conditions
  • Metabolic Syndrome
  • Stress Oxidative
  • Inflammation
  • Healthy Subjects

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Fasting Eicosanoids
Fasting glucose
Fasting insulin
+5 more
Secondary outcome measures
Aerobic Fitness
Blood Pressure
Body Mass Index
+2 more
Other outcome measures
Acute Diet
Habitual Diet
Physical activity and sedentary behavior

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Low dose CSOExperimental Treatment1 Intervention
Participants will be randomly assigned to a smoothie containing 30 g of CSO per day for four weeks.They will be asked to consume smoothies any time of the day.
Group II: High dose CSOExperimental Treatment1 Intervention
Participants will be randomly assigned to a smoothie containing 60 g of CSO per day for four weeks.They will be asked to consume smoothies any time of the day.
Group III: High dose OOActive Control1 Intervention
Participants will be randomly assigned to a smoothie containing 60 g of OO per day for four weeks.They will be asked to consume smoothies any time of the day.
Group IV: Low dose OOActive Control1 Intervention
Participants will be randomly assigned to a smoothie containing 30 g of OO per day for four weeks.They will be asked to consume smoothies any time of the day.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Low dose CSO
2022
N/A
~50
High dose CSO
2022
N/A
~50

Find a Location

Who is running the clinical trial?

Montana State UniversityLead Sponsor
44 Previous Clinical Trials
1,043,797 Total Patients Enrolled
1 Trials studying Metabolic Syndrome
40 Patients Enrolled for Metabolic Syndrome
Mary P. Miles, PhDPrincipal InvestigatorMontana State University

Media Library

High dose CSO Clinical Trial Eligibility Overview. Trial Name: NCT05439590 — N/A
Metabolic Syndrome Research Study Groups: High dose OO, Low dose OO, Low dose CSO, High dose CSO
Metabolic Syndrome Clinical Trial 2023: High dose CSO Highlights & Side Effects. Trial Name: NCT05439590 — N/A
High dose CSO 2023 Treatment Timeline for Medical Study. Trial Name: NCT05439590 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are researchers still accepting enrollees for this research project?

"Affirmative. According to clinicaltrials.gov, the research trial which was first unveiled on August 8th 2022 is actively recruiting participants and desires 32 people at 1 medical centre."

Answered by AI

Could you elucidate the total amount of participants involved in this investigation?

"Affirmative. The data hosted on clinicaltrials.gov displays that this medical trial, which was unveiled on August 8th 2022, is currently recruiting participants. Thirty-two people need to be enrolled from 1 site in the study."

Answered by AI

Is this experiment welcoming participants aged 45 or over?

"This research is actively recruiting patients aged 18 to 55 years old."

Answered by AI

Who would be an ideal candidate for enrollment in this clinical research?

"This medical experiment is recruiting 32 individuals, aged 18-55 and who have metabolic syndrome. Furthermore, for inclusion in the trial participants must also satisfy a body mass index within the range of 18-27 kg/m2."

Answered by AI

What is the desired consequence of this experiment?

"This assessment will span a period of 4 weeks and its primary goal is to measure fasting serum lipids. Secondary outcomes include measuring the visceral adipose tissue in liters, body composition as a percent fat, and blood pressure denoted with systolic/diastolic measurements (mmHg)."

Answered by AI
~18 spots leftby Apr 2025