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Brain Stimulation

Brain Stimulation for PTSD

N/A
Recruiting
Led By Wen Li, PhD
Research Sponsored by Florida State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline/pre- to immediately post-tacs
Awards & highlights

Study Summary

This trial aims to create a new understanding of PTSD by looking at how 3 parts of the brain work together.

Who is the study for?
This trial is for right-handed individuals aged 18-50 with normal vision and smell, who meet specific safety criteria. Participants must have a PTSD diagnosis and if on psychotropic meds, they should be stable for the last 2 months. Substance users must abstain for 48 hours before the experiment.Check my eligibility
What is being tested?
The study tests a new theory of PTSD involving sensory cortex and amygdala-PFC dysfunctions by using two brain stimulation techniques: alpha-frequency tACS (transcranial alternating current stimulation) and random noise stimulation.See study design
What are the potential side effects?
Potential side effects from the brain stimulations could include mild discomfort at the electrode site, headache, dizziness or nausea during or after treatment. However, these are generally rare and temporary.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline/pre- to immediately post-tacs
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline/pre- to immediately post-tacs for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Neural response in the SPA circuitry
Secondary outcome measures
Salience detection and vigilance behavior

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: With PTSD for studyExperimental Treatment2 Interventions
80 patients with PTSD in randomized, double-blind, controlled design
Group II: Health controls for studyActive Control2 Interventions
80 healthy subjects in randomized, double-blind, controlled design

Find a Location

Who is running the clinical trial?

Florida State UniversityLead Sponsor
200 Previous Clinical Trials
31,598 Total Patients Enrolled
Wen Li, PhDPrincipal InvestigatorFlorida State University
2 Previous Clinical Trials
51 Total Patients Enrolled

Media Library

alpha-frequency tACS (Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT05895006 — N/A
Post-Traumatic Stress Disorder Research Study Groups: With PTSD for study, Health controls for study
Post-Traumatic Stress Disorder Clinical Trial 2023: alpha-frequency tACS Highlights & Side Effects. Trial Name: NCT05895006 — N/A
alpha-frequency tACS (Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05895006 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has recruitment for this clinical trial ceased or is enrollment still open?

"According to the records on clinicaltrials.gov, recruitment for this trial is still ongoing. The study was first published on April 1st 2023 and then subsequently updated on May 30th 2023."

Answered by AI

Does this clinical experiment open its doors to those aged 45 and above?

"This medical trial only allows for patients aged 18 to 50 to join. There are 40 seperate studies offered to those younger than 18 and 327 that cater to the elderly population over 65 years old."

Answered by AI

What is the current enrollment count for this clinical research?

"Yes, according to clinicaltrials.gov the trial is still recruiting participants. This study was first announced on April 1st 2023 and last updated May 30th 2023. 160 patients are being sought after from a single site."

Answered by AI

What criteria must participants satisfy to be eligible for this research endeavor?

"Prospective candidates must have post-traumatic stress disorder and be between 18 to 50 years old in order to apply for this experiment. Altogether, the study is taking on 160 patients."

Answered by AI

Who else is applying?

What state do they live in?
Florida
What site did they apply to?
Leon County
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0
Recent research and studies
clinicaltrials.govStudy
A Neurosensory Account
Wen Li 2023. "A Neurosensory Account". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05895006.
~96 spots leftby May 2026
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