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Non-invasive Brain Stimulation

Active Stimulation for Post-Traumatic Stress Disorder (TAVRE Trial)

N/A

Waitlist Available

Led By Noah S. Philip, MD

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 month

Awards & highlights

TAVRE Trial Summary

This trial will test whether a combination of transcranial direct current stimulation (tDCS) and virtual reality exposure can effectively treat Veterans with chronic PTSD. If successful, this could lead to a new non-medication approach to treating the condition.

Eligible Conditions

Post Traumatic Stress Disorder

TAVRE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 month

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 month

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Post-Traumatic Stress Disorder

Psychophysiology (Skin Conductance Reactivity; SCR)

Quality of Life Enjoyment and Satisfaction Questionnaire (QLESQ)

TAVRE Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Active StimulationActive Control2 Interventions

Active stimulation (tDCS) will be used in the dose of 2mA /25 min per day, for 6 sessions over the course of 2 weeks (3 sessions per week).

Group II: Sham StimulationPlacebo Group2 Interventions

Sham tDCS uses the device study mode (10 µA over 15 ms current pulse applied every 550 ms, 3ms peak current). This process will be used for each of the 6 sessions during a 2 week period.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,609 Previous Clinical Trials

3,306,538 Total Patients Enrolled

Noah S. Philip, MDPrincipal InvestigatorProvidence VA Medical Center, Providence, RI

2 Previous Clinical Trials

98 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age limitation for this experiment greater than 45 years?

"In order to be considered eligible for this clinical trial, applicants must between 18 and 70 years of age. However, there are 46 studies that accept minors and 329 trials open to seniors over 65."

Answered by AI

What is the estimated number of participants included in this research project?

"Affirmative. Clinicaltrials.gov lists this clinical trial as actively seeking participants, with the first posting on April 2nd 2018 and most recent edit occurring on January 12th 2022. The research is expecting 90 individuals to be recruited from a single site."

Answered by AI

Are there vacancies in this clinical trial for participants?

"Affirmative. According to data available on clinicaltrials.gov, this study is actively enrolling participants. The trial was initially posted on April 2nd 2018 and most recently modified on January 12th 2022, with the aim of recruiting 90 individuals from a single location."

Answered by AI

How can I participate in this clinical research?

"This study seeks 90 individuals suffering from post-traumatic stress disorder (PTSD), and aged between 18 to 70 years old. Crucially, applicants must be a veteran with an official DSM-5 diagnosis of chronic PTSD; their condition should remain symptomatic despite consistent treatment for the past 6 weeks prior to enrolling in the trial. Potential participants are asked to demonstrate that they can fulfill all related procedures and visits as required."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

tDCS Plus Virtual Reality for PTSD

2018. "tDCS Plus Virtual Reality for PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03372460.