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Exposure for Post-Traumatic Stress Disorder

N/A

Waitlist Available

Research Sponsored by University of Texas at Austin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up one month follow-up assessment

Awards & highlights

Study Summary

This trial is investigating whether or not antagonistic actions (such as adopting an open posture, eating a palatable snack, smiling, or wishing on high levels of emotional distress) can help to enhance emotional processing during exposure to trauma-relevant stimuli, in order to improve treatment outcome for PTSD.

Eligible Conditions

Post Traumatic Stress Disorder

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ one month follow-up assessment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~one month follow-up assessment

This trial's timeline: 3 weeks for screening, Varies for treatment, and one month follow-up assessment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Posttraumatic Stress Disorder Scale (PCL-5)

Secondary outcome measures

Coping Self-Efficacy (CSE-T-SF)

Post-Traumatic Stress Disorder

PTSD-Relevant Threat Appraisals (PTA)

+1 more

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Psychoeducation & exposure/Antagonistic Actions (PSYED+EXP+AA)Experimental Treatment2 Interventions

The participant will receive both PDF and video materials involving psychoeducational materials on trauma and safety behaviors. The participant will then be instructed to start the trauma video clip exposures. There will be six 3-minute video exposure trials with an inter-trial interval of 2 minutes, during which participants will complete ratings of (a) peak subjective distress during the trauma-videoclip; (b) anticipated subjective distress for the next trial; and (c) level of confidence for coping with their own trauma memory should it become activated. Antagonistic action strategies during exposure to the trauma-videoclips will include (a) adopting an open posture; (b) eating a palatable snack; (c) smiling; and (d) wishing on high levels of emotional distress (e.g., "come on distress hit me with your best shot"). The participant will engage in all of the four antagonistic actions for the six exposure trials.

Group II: Psychoeducation followed by exposure (PSYED+EXP)Active Control2 Interventions

Group III: Psychoeducation alone (PSYED)Placebo Group1 Intervention

The participant will receive both PDF and video materials involving psychoeducational materials on trauma and safety behaviors.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Psychoeducation

2005

Completed Phase 2

~3310

Exposure

2018

Completed Phase 1

~1780

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Texas at AustinLead Sponsor

350 Previous Clinical Trials

80,910 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are persons aged 70 and below able to participate in this experiment?

"This trial has a limited age range for qualified applicants, encompassing individuals between 18 and 60 years old. Patients younger than the prescribed cutoff can look into 46 alternative studies while patients above 65 may enroll in 328 different clinical trials."

Answered by AI

Does the research team still need participants for this trial?

"According to current information on clinicaltrials.gov, the trial opened for recruitment on March 22nd 2021 and is still actively seeking participants as of June 8th 2022."

Answered by AI

Are there any restrictions regarding the total enrollment of this research project?

"Affirmative. According to clinicaltrials.gov, this research endeavor is in the process of recruiting participants. This trial was first listed on March 22nd 2021 and was most recently updated on June 8th 2022 with a goal of enrolling 84 patients at 1 site."

Answered by AI

Do I meet the prerequisites for participation in this experiment?

"This clinical trial seeks 84 patients aged between 18 to 60 with post traumatic stress disorder (PTSD). In order to qualify, individuals must be able to prove they experienced an assault, motor vehicle accident or combat related trauma as documented on the LEC-5. Furthermore, participants need access to internet and should speak English fluently. Additionally, consent forms have to be signed and no external treatment for PTSD is allowed during the study period."

Answered by AI