← Back to Search

Behavioral Intervention

Cognitive Processing Therapy for Post-Traumatic Stress Disorder

N/A

Waitlist Available

Led By Jennifer Wachen, Ph.D.

Research Sponsored by VA Boston Healthcare System

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, one-month posttreatment, 4 months posttreatment (weeks 0, 5, 10, 17, 22, depending on tx condition)

Awards & highlights

Study Summary

This trial will compare the effectiveness of two different treatments for PTSD delivered in different intensities (massed vs. standard).

Eligible Conditions

Post-Traumatic Stress Disorder

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, one-month posttreatment, 4 months posttreatment (weeks 0, 5, 10, 17, 22, depending on tx condition)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, one-month posttreatment, 4 months posttreatment (weeks 0, 5, 10, 17, 22, depending on tx condition)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, one-month posttreatment, 4 months posttreatment (weeks 0, 5, 10, 17, 22, depending on tx condition) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in PTSD symptoms as assessed by the Clinician Administered PTSD Scale (CAPS-5)

Change in PTSD symptoms as assessed by the PTSD Check List - DSM-5 (PCL-5)

Secondary outcome measures

Change in depressive symptoms as measured by the Patient Health Questionnaire-9 (PHQ-9)

Change in sleep disturbance as measured by the Insomnia Severity Index (ISI)

Change in somatic symptoms as measured by the Patient Health Questionnaire - 15 (PHQ-15)

+5 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Massed Cognitive Processing Therapy (MCPT)Experimental Treatment1 Intervention

Cognitive Processing Therapy is an evidence-based form of Cognitive Behavioral Therapy (CBT) used to treat PTSD. CPT is a 12-session manualized program that focuses on challenging beliefs and assumptions related to the trauma, oneself, and the world. MCPT will be delivered in an intensive outpatient setting (12 sessions in 5 days) composed of both group and individual sessions.

Group II: Standard Cognitive Processing TherapyActive Control1 Intervention

Cognitive Processing Therapy is an evidence-based form of Cognitive Behavioral Therapy (CBT) used to treat PTSD. CPT is a 12-session manualized program that focuses on challenging beliefs and assumptions related to the trauma, oneself, and the world. Standard CPT will be delivered in 12 one-hour sessions over 6 weeks and involves only individual sessions.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cognitive Processing Therapy

2016

N/A

~3400

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

VA Boston Healthcare SystemLead Sponsor

68 Previous Clinical Trials

970,312 Total Patients Enrolled

Fort Belvoir Community HospitalFED

13 Previous Clinical Trials

2,004 Total Patients Enrolled

The University of Texas Health Science Center at San AntonioOTHER

453 Previous Clinical Trials

91,290 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the ambitious goal of this research endeavor?

"The primary metric of this actionable research is Change in PTSD symptoms, as evaluated by the Clinician Administered PTSD Scale (CAPS-5). Secondary outcomes are gauged through examining changes to depressive symptoms measured with the Patient Health Questionnaire-9 (PHQ-9), anger assessed via Dimensions of Anger Reactions-5 (DAR-5) and suicidality tracked on Depressive Symptom Index - Suicidality Subscale (DSI-SS). These parameters will be observed at Baseline, one month posttreatment, 4 months posttreatment and weekly/daily throughout treatment."

Answered by AI

Could someone apply to participate in this trial at present?

"Clinicaltrials.gov reports that this medical trial has not been recruiting since September 21st 2022 and is, as of now, no longer searching for candidates. Yet despite this, there are currently 417 other clinical trials actively looking for patients to participate in their research."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Massed Cognitive Processing Therapy for Combat-related PTSD

Jennifer Schuster Wachen, Ph.D. 2019. "Massed Cognitive Processing Therapy for Combat-related PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03808727.