Weekly Emotional Disclosure (WED) for Post Traumatic Stress Disorder (PTSD)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Post Traumatic Stress Disorder (PTSD)+2 More
Weekly Emotional Disclosure (WED) - Behavioral
Eligibility
18+
Female
What conditions do you have?
Select

Study Summary

This trial will test if writing about past traumas can help women with PTSD.

Eligible Conditions
  • Post Traumatic Stress Disorder (PTSD)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 3 Secondary · Reporting Duration: Baseline, 6 weeks

Baseline, 6 weeks
Change in PTSD symptoms as assessed by the Impact of Event Scale
Change in functional connectivity of the Default Mode Network (DMN)
Change in salivary adrenal corticotrophin releasing hormone (ACTH) levels
Change in salivary alpha amylase (sAA) levels
Change in verbal learning as assessed by Hopkins Verbal Learning Task (HVLT)

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

Non-Trauma Daily Event Writing in Spanish Group
1 of 3
Spanish-Only Writing Group
1 of 3
English-Only Writing Group
1 of 3
Experimental Treatment

36 Total Participants · 3 Treatment Groups

Primary Treatment: Weekly Emotional Disclosure (WED) · No Placebo Group · N/A

Non-Trauma Daily Event Writing in Spanish Group
Behavioral
Experimental Group · 1 Intervention: Weekly Emotional Disclosure (WED) · Intervention Types: Behavioral
Spanish-Only Writing Group
Behavioral
Experimental Group · 1 Intervention: Weekly Emotional Disclosure (WED) · Intervention Types: Behavioral
English-Only Writing Group
Behavioral
Experimental Group · 1 Intervention: Weekly Emotional Disclosure (WED) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 6 weeks

Who is running the clinical trial?

University of MiamiLead Sponsor
787 Previous Clinical Trials
384,374 Total Patients Enrolled
5 Trials studying Post Traumatic Stress Disorder (PTSD)
357 Patients Enrolled for Post Traumatic Stress Disorder (PTSD)
Center for Latino Health Research OpportunitiesUNKNOWN
Roger McIntoshPrincipal InvestigatorUniversity of Miami

Eligibility Criteria

Age 18+ · Female Participants · 8 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are willing and able to sign ICF.\n
You are a Spanish speaker or English speaker.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 24th, 2021

Last Reviewed: October 28th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

Who else is applying?

What state do they live in?
Florida33.3%
Georgia33.3%
Tennessee33.3%
How old are they?
65+50.0%
18 - 6550.0%
What site did they apply to?
University of Miami100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%